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EphA4 Protein, Human, Recombinant (hFc)

Catalog No. TMPJ-00405
Synonyms: Ephrin type-A receptor 4, SEK, hEK8, TYRO1, Tyrosine-protein kinase receptor SEK, EPHA4, Tyrosine-protein kinase TYRO1, EPH-like kinase 8, EK8

Ephrin type-A receptor 4(EPHA4) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHA4 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
EphA4 Protein, Human, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 110.00
50 μg 5 days $ 310.00
500 μg 5 days $ 1,300.00
1 mg 5 days $ 1,980.00
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Biological Description
Technical Params
Product Properties
Description Ephrin type-A receptor 4(EPHA4) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHA4 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Species Human
Expression System Human Cells
Tag C-Fc
Accession Number P54764
Synonyms Ephrin type-A receptor 4, SEK, hEK8, TYRO1, Tyrosine-protein kinase receptor SEK, EPHA4, Tyrosine-protein kinase TYRO1, EPH-like kinase 8, EK8
Amino Acid Val20-Thr547
Construction Recombinant Human Ephrin Type A Receptor 4 is produced by our Mammalian expression system and the target gene encoding Val20-Thr547 is expressed with a human IgG1 Fc tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 90-120 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Ephrin type-A receptor 4(EPHA4) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHA4 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

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Keywords

EphA4 Protein, Human, Recombinant (hFc) Ephrin type-A receptor 4 SEK hEK8 TYRO1 TYRO-1 Tyrosine-protein kinase receptor SEK EPHA 4 EK 8 TYRO 1 EPHA-4 EPHA4 Tyrosine-protein kinase TYRO1 EPH-like kinase 8 EK8 EK-8 recombinant recombinant-proteins proteins protein

 

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