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L-Palmitoylcarnitine TFA

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Catalog No. T73764

L-Palmitoylcarnitine TFA, a long-chain acylcarnitine and fatty acid metabolite, accumulates in the sarcolemma and disrupts the membrane lipid environment during ischemia. It inhibits K ATP channel activity by interacting with Kir6.2 without altering single-channel conductance [1].

L-Palmitoylcarnitine TFA
Other Forms of L-Palmitoylcarnitine TFA:

L-Palmitoylcarnitine TFA

😃Good
Catalog No. T73764
L-Palmitoylcarnitine TFA, a long-chain acylcarnitine and fatty acid metabolite, accumulates in the sarcolemma and disrupts the membrane lipid environment during ischemia. It inhibits K ATP channel activity by interacting with Kir6.2 without altering single-channel conductance [1].
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2 mg$345 days5 days
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Product Introduction

Bioactivity
Description
L-Palmitoylcarnitine TFA, a long-chain acylcarnitine and fatty acid metabolite, accumulates in the sarcolemma and disrupts the membrane lipid environment during ischemia. It inhibits K ATP channel activity by interacting with Kir6.2 without altering single-channel conductance [1].
Chemical Properties
Molecular Weight513.63
FormulaC25H46F3NO6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (194.69 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (6.42 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9469 mL9.7346 mL19.4693 mL97.3463 mL
5 mM0.3894 mL1.9469 mL3.8939 mL19.4693 mL
10 mM0.1947 mL0.9735 mL1.9469 mL9.7346 mL
20 mM0.0973 mL0.4867 mL0.9735 mL4.8673 mL
50 mM0.0389 mL0.1947 mL0.3894 mL1.9469 mL
100 mM0.0195 mL0.0973 mL0.1947 mL0.9735 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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