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Anti-GOT2 Antibody (2H61)
😃Good
Catalog No. TMAY-00223
Alias mitAAT, mAspAT, KYAT4, KATIV, KAT4, DEE82
Anti-GOT2 Antibody (2H61) is a Mouse antibody targeting GOT2. Anti-GOT2 Antibody (2H61) can be used in IHC-P.
Anti-GOT2 Antibody (2H61)
Anti-GOT2 Antibody (2H61)
😃Good
Catalog No. TMAY-00223Alias mitAAT, mAspAT, KYAT4, KATIV, KAT4, DEE82
Anti-GOT2 Antibody (2H61) is a Mouse antibody targeting GOT2. Anti-GOT2 Antibody (2H61) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: IHC-P Reactivity: Human |
| Alias | mitAAT, mAspAT, KYAT4, KATIV, KAT4, DEE82 |
| Ig Type | Mouse IgG1 |
| Clone | 2H61 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human GOT2 in human liver with mouse monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human GOT2 in human hepatoma with mouse monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:50-1:200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the C-terminus of the Human GOT2. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | GOT2 (Glutamic-Oxaloacetic Transaminase 2) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The encoded protein is a mitochondrial enzyme that oxidizes glutamate to produce alpha-ketoglutarate for the Krebs cycle, eventually leading to the production of adenosine triphosphate (ATP). GOT2 belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. GOT2-mediated ATP synthesis may be a pivotal mechanism underlying the protective effect of febuxostat against neurodegeneration in experimental autoimmune encephalomyelitis (EAE). The high aberrant GOT2 expression is prognostic in diffuse large B-cell lymphoma. GOT2 is broadly expressed in the heart, liver, and other tissues. Diseases associated with GOT2 include Epileptic Encephalopathy, Early Infantile, 82, and Acute Vascular Insufficiency Of Intestine. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: C-terminus of the Human GOT2 |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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