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Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10)
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Catalog No. T9901A-542
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) is a mouse-derived antibody that targets and inhibits mouse, rat, and human Osteopontin/SPP1. It significantly suppresses tumour growth in CT26 and MC38 mouse tumour models and attenuates VSMC migration.
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10)
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10)
😃Good
Purity: 95%
Catalog No. T9901A-542
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) is a mouse-derived antibody that targets and inhibits mouse, rat, and human Osteopontin/SPP1. It significantly suppresses tumour growth in CT26 and MC38 mouse tumour models and attenuates VSMC migration.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $182 | - | In Stock | |
| 5 mg | $539 | - | In Stock | |
| 10 mg | $863 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95%
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| Description | Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) is a mouse-derived antibody that targets and inhibits mouse, rat, and human Osteopontin/SPP1. It significantly suppresses tumour growth in CT26 and MC38 mouse tumour models and attenuates VSMC migration. |
| In vitro | Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10), when applied to cardiac fibroblasts at concentrations of 7.2 μg/mL or 72 ng/mL for 30 minutes, can block angiotensin II-induced DNA synthesis [2]. Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10), when acting on cardiac fibroblasts at concentrations of 7.2 μg/mL or 25 μg/mL for 30 minutes, can inhibit collagen gel contraction co-induced by angiotensin II and osteopontin [2]. Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10), when applied to A10 cells at a concentration of 100 ng/mL for 48 hours, significantly attenuates high mobility group box 1 (HMGB1)-induced migration of vascular smooth muscle cells (VSMCs) [3]. |
| In vivo | Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) was administered intraperitoneally to mice at a dose of 500 μg per mouse, with dosing every 2 days for a total of 10 days. This treatment significantly inhibited tumor growth in CT26 or MC38 mouse tumor models [1]. |
| Clone | MPIIIB10 |
| Reactivity | Mouse/Rat/Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Osteopontin/SPP1 |
| Molecular Weight | 150 kDa |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Mouse IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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