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Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10)
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Catalog No. T9901A-542
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) is a mouse-derived antibody that targets and inhibits mouse, rat, and human Osteopontin/SPP1. It significantly suppresses tumour growth in CT26 and MC38 mouse tumour models and attenuates VSMC migration.
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10)
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10)
😃Good
Purity: 95%
Catalog No. T9901A-542
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) is a mouse-derived antibody that targets and inhibits mouse, rat, and human Osteopontin/SPP1. It significantly suppresses tumour growth in CT26 and MC38 mouse tumour models and attenuates VSMC migration.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $182 | - | In Stock | |
| 5 mg | $539 | - | In Stock | |
| 10 mg | $863 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95%
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Product Introduction
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Chemical Properties
| Description | Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) is a mouse-derived antibody that targets and inhibits mouse, rat, and human Osteopontin/SPP1. It significantly suppresses tumour growth in CT26 and MC38 mouse tumour models and attenuates VSMC migration. |
| In vitro | Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10), when applied to cardiac fibroblasts at concentrations of 7.2 μg/mL or 72 ng/mL for 30 minutes, can block angiotensin II-induced DNA synthesis [2]. Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10), when acting on cardiac fibroblasts at concentrations of 7.2 μg/mL or 25 μg/mL for 30 minutes, can inhibit collagen gel contraction co-induced by angiotensin II and osteopontin [2]. Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10), when applied to A10 cells at a concentration of 100 ng/mL for 48 hours, significantly attenuates high mobility group box 1 (HMGB1)-induced migration of vascular smooth muscle cells (VSMCs) [3]. |
| In vivo | Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) was administered intraperitoneally to mice at a dose of 500 μg per mouse, with dosing every 2 days for a total of 10 days. This treatment significantly inhibited tumor growth in CT26 or MC38 mouse tumor models [1]. |
| Clone | MPIIIB10 |
| Reactivity | Mouse/Rat/Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | ＜ 1.0 EU/mg |
| Conjucates | Unconjugated |
| Color | Transparent |
| Appearance | Liquid |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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