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Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10)

Catalog No. T9901A-542 Copy Product Info
Purity: 95%
🥰Excellent
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) is a mouse-derived antibody that targets and inhibits mouse, rat, and human Osteopontin/SPP1. It significantly suppresses tumour growth in CT26 and MC38 mouse tumour models and attenuates VSMC migration.

Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10)

Copy Product Info
🥰Excellent
Catalog No. T9901A-542

Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) is a mouse-derived antibody that targets and inhibits mouse, rat, and human Osteopontin/SPP1. It significantly suppresses tumour growth in CT26 and MC38 mouse tumour models and attenuates VSMC migration.

Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody
(MPIIIB10)
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$182-In Stock
5 mg$539-In Stock
10 mg$863-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) is a mouse-derived antibody that targets and inhibits mouse, rat, and human Osteopontin/SPP1. It significantly suppresses tumour growth in CT26 and MC38 mouse tumour models and attenuates VSMC migration.
In vitro
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10), when applied to cardiac fibroblasts at concentrations of 7.2 μg/mL or 72 ng/mL for 30 minutes, can block angiotensin II-induced DNA synthesis [2].
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10), when acting on cardiac fibroblasts at concentrations of 7.2 μg/mL or 25 μg/mL for 30 minutes, can inhibit collagen gel contraction co-induced by angiotensin II and osteopontin [2].
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10), when applied to A10 cells at a concentration of 100 ng/mL for 48 hours, significantly attenuates high mobility group box 1 (HMGB1)-induced migration of vascular smooth muscle cells (VSMCs) [3].
In vivo
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) was administered intraperitoneally to mice at a dose of 500 μg per mouse, with dosing every 2 days for a total of 10 days. This treatment significantly inhibited tumor growth in CT26 or MC38 mouse tumor models [1].
Clone
MPIIIB10
Reactivity
Mouse/Rat/Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetOsteopontin/SPP1
Chemical Properties
Molecular Weight150 kDa
Antibody Information
IsotypeMouse IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice.

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