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Anti-CD16/FCGR3 Antibody-APC (6Q305)
🥰Excellent
Catalog No. TMAY-00741A
Anti-CD16/FCGR3 Antibody-APC (6Q305) is a APC-conjugated Mouse antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody-APC (6Q305) can be used in FCM.
Anti-CD16/FCGR3 Antibody-APC (6Q305)
Anti-CD16/FCGR3 Antibody-APC (6Q305)
🥰Excellent
Catalog No. TMAY-00741A
Anti-CD16/FCGR3 Antibody-APC (6Q305) is a APC-conjugated Mouse antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody-APC (6Q305) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD16/FCGR3 Antibody-APC (6Q305) is a APC-conjugated Mouse antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody-APC (6Q305) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 6Q305 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CD16 expression on human whole blood lymphocytes. Cells were stained with APC-conjugated anti-Human CD16. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD16a/Fc gamma RIIIa (rh CD16a/Fc gamma RIIIa; TMPY-00763; P08637-1; Met1-Gln208,176F) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes. |
| Conjucates | APC |
| Others Formats | Unconjugated/PerCP/FITC/PE |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Human CD16a/Fc gamma RIIIa Protein (TMPY-00763) |
| Antigen Species | Human |
| Biology Area | Fc Receptors |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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