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D-(-)-3-Phosphoglyceric acid disodium

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Catalog No. T37185Cas No. 80731-10-8
Alias 3-Phospho-D-glyceric acid disodium

D-(-)-3-Phosphoglyceric acid disodium (3-Phospho-D-glyceric acid disodium) is an intermediate in glycolysis/gluconeogenesis and the biosynthesis of serine, glycine, and threonine, competitively inhibiting yeast enolase. It also functions as an intermediate in biosynthetic pathways in plants, eukaryotes, and prokaryotes.

D-(-)-3-Phosphoglyceric acid disodium

D-(-)-3-Phosphoglyceric acid disodium

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Purity: 99.97%
Catalog No. T37185Alias 3-Phospho-D-glyceric acid disodiumCas No. 80731-10-8
D-(-)-3-Phosphoglyceric acid disodium (3-Phospho-D-glyceric acid disodium) is an intermediate in glycolysis/gluconeogenesis and the biosynthesis of serine, glycine, and threonine, competitively inhibiting yeast enolase. It also functions as an intermediate in biosynthetic pathways in plants, eukaryotes, and prokaryotes.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$30In StockIn Stock
5 mg$64In StockIn Stock
10 mg$106In StockIn Stock
25 mg$213In StockIn Stock
50 mg$338In StockIn Stock
100 mg$538In StockIn Stock
200 mg$766-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.97%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
D-(-)-3-Phosphoglyceric acid disodium (3-Phospho-D-glyceric acid disodium) is an intermediate in glycolysis/gluconeogenesis and the biosynthesis of serine, glycine, and threonine, competitively inhibiting yeast enolase. It also functions as an intermediate in biosynthetic pathways in plants, eukaryotes, and prokaryotes.
In vitro
D-(-)-3-Phosphoglyceric acid disodium competitively inhibits yeast enolase. The enzyme-Mg2+ complex was thermally titrated with 3-phosphoglyceric acid.The heat absorbed when 3-phosphoglyceric acid binds to enolase has been measured in Tris, in Hepes, and in Pipes at the same enzyme, metal, and inhibitor concentrations[1].
Synonyms3-Phospho-D-glyceric acid disodium
Chemical Properties
Molecular Weight230.02
FormulaC3H5Na2O7P
Cas No.80731-10-8
SmilesC([C@H](C(=O)[O-])O)OP(=O)(O)[O-].[Na+].[Na+]
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
PBS (pH 7.2): 10 mg/mL (43.47 mM), Sonication is recommended.
H2O: 242.5 mg/mL (1054.26 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/H2O
1mg5mg10mg50mg
1 mM4.3474 mL21.7372 mL43.4745 mL217.3724 mL
5 mM0.8695 mL4.3474 mL8.6949 mL43.4745 mL
10 mM0.4347 mL2.1737 mL4.3474 mL21.7372 mL
20 mM0.2174 mL1.0869 mL2.1737 mL10.8686 mL
H2O
1mg5mg10mg50mg
50 mM0.0869 mL0.4347 mL0.8695 mL4.3474 mL
100 mM0.0435 mL0.2174 mL0.4347 mL2.1737 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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