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Retinyl palmitate

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Catalog No. T1059Cas No. 79-81-2
Alias Vitamin A palmitate, Retinyl (Vitamin A) Palmitate, Retinol palmitate

Retinyl palmitate (Vitamin A palmitate) is a naturally-occurring phenyl analogue of retinol, with potential antineoplastic and chemopreventive activities.

Retinyl palmitate

Retinyl palmitate

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Catalog No. T1059Alias Vitamin A palmitate, Retinyl (Vitamin A) Palmitate, Retinol palmitateCas No. 79-81-2
Retinyl palmitate (Vitamin A palmitate) is a naturally-occurring phenyl analogue of retinol, with potential antineoplastic and chemopreventive activities.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mg$30In StockIn Stock
100 mg$42In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Potency:1600-1800 kU/g
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Retinyl palmitate (Vitamin A palmitate) is a naturally-occurring phenyl analogue of retinol, with potential antineoplastic and chemopreventive activities.
In vitro
The microencapsulation of vitamin A palmitate by gelatin-acacia complex is a promising method for converting an oily vitamin to solid powders for an aid to handling and ease of incorporation in preparations. [1]
In vivo
Vitamin A Palmitate (80 mg/kg daily p.o.) or (800 mg/kg once a week p.o.) dose-dependently decreases the size of papillomas in mice, the daily administration induces a somewhat higher extent of regression than the weekly application if the total doses are compared. Water miscible solutions of Vitamin A Palmitate as well as of Vitamin A acid given by the oral route elicit the same effect on papillomas. [2] Vitamin A Palmitate (A single simultaneous injection of 150 g) enhances cell-mediated immunity to sheep red blood cells(SRBC) as early as 3 days following immunization, and the enhancement persists for at least 3 weeks. [3]
SynonymsVitamin A palmitate, Retinyl (Vitamin A) Palmitate, Retinol palmitate
Chemical Properties
Molecular Weight524.86
FormulaC36H60O2
Cas No.79-81-2
SmilesCCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C
Relative Density.0.92 g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 250 mg/mL (476.32 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9053 mL9.5263 mL19.0527 mL95.2635 mL
5 mM0.3811 mL1.9053 mL3.8105 mL19.0527 mL
10 mM0.1905 mL0.9526 mL1.9053 mL9.5263 mL
20 mM0.0953 mL0.4763 mL0.9526 mL4.7632 mL
50 mM0.0381 mL0.1905 mL0.3811 mL1.9053 mL
100 mM0.0191 mL0.0953 mL0.1905 mL0.9526 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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