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Anti-MAVS Polyclonal Antibody
(Synonyms: VISA, Virus induced signaling adapter, Putative NF kappa B activating protein 031N, Mitochondrial Antiviral Signaling, Mitochondrial anti viral signaling protein, MGC3260, MAVS, KIAA1271, IPS-1, IPS1, Ips 1, Interferon-beta promoter stimulator protein 1, Interferon β promoter stimulator protein 1, FLJ41962, FLJ38051, FLJ35386, FLJ31698, FLJ27482, DKFZp666M015, DKFZp547C224, CARDIF, CARD adapter inducing interferon beta) Copy Product Info
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Synonyms: VISA, Virus induced signaling adapter, Putative NF kappa B activating protein 031N, Mitochondrial Antiviral Signaling, Mitochondrial anti viral signaling protein, MGC3260, MAVS, KIAA1271, IPS-1, IPS1, Ips 1, Interferon-beta promoter stimulator protein 1, Interferon β promoter stimulator protein 1, FLJ41962, FLJ38051, FLJ35386, FLJ31698, FLJ27482, DKFZp666M015, DKFZp547C224, CARDIF, CARD adapter inducing interferon beta
Catalog No. TMAB-01107 Copy Product Info
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Anti-MAVS Polyclonal Antibody is a Rabbit antibody targeting MAVS. Anti-MAVS Polyclonal Antibody can be used in WB.
Anti-MAVS Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $221 | 7-10 days | 7-10 days | |
| 100 µL | $374 | 7-10 days | 7-10 days | |
| 200 µL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-MAVS Polyclonal Antibody is a Rabbit antibody targeting MAVS. Anti-MAVS Polyclonal Antibody can be used in WB. |
| Synonyms | VISA, Virus induced signaling adapter, Putative NF kappa B activating protein 031N, Mitochondrial Antiviral Signaling, Mitochondrial anti viral signaling protein, MGC3260, MAVS, KIAA1271, IPS-1, IPS1, Ips 1, Interferon-beta promoter stimulator protein 1, Interferon β promoter stimulator protein 1, FLJ41962, FLJ38051, FLJ35386, FLJ31698, FLJ27482, DKFZp666M015, DKFZp547C224, CARDIF, CARD adapter inducing interferon beta |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Cow) |
| Verified Activity | Sample: Liver (Mouse) Lysate at 40 μg Primary: Anti-MAVS (TMAB-01107) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kDa Observed band size: 56 kDa  |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion outer membrane. |
| Tissue Specificity | Present in T-cells, monocytes, epithelial cells and hepatocytes (at protein level). Ubiquitously expressed, with highest levels in heart, skeletal muscle, liver, placenta and peripheral blood leukocytes. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | MAVS (Mitochondrial Antiviral Signaling) mediates the activation of NF-kappaB and IRF3 in response to antiviral infection. Silencing of MAVS expression permits derepression of viral replication, while over expression of MAVS boosts antiviral immunity. |
| Immunogen | KLH conjugated synthetic peptide: human MAVS N terminus |
| Antigen Species | Human |
| Gene Name | MAVS |
| Gene ID | |
| Protein Name | Mitochondrial antiviral-signaling protein |
| Uniprot ID | |
| Biology Area | NFkB pathway,Antiviral Signaling,NFkB Pathway |
| Function | Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis. |
| Molecular Weight | Theoretical: 56 kDa. Actual: 56 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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