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Opaviraline (GW-420867X) is a potent reverse transcriptase inhibitor that inhibits Human immunodeficiency virus 1 and has the potential to treat HIV infection.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $397 | In Stock | In Stock | |
| 5 mg | $970 | In Stock | In Stock | |
| 10 mg | $1,290 | In Stock | In Stock | |
| 25 mg | $1,950 | In Stock | In Stock | |
| 50 mg | $2,620 | In Stock | In Stock | |
| 100 mg | $3,530 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $867 | In Stock | In Stock |
| Description | Opaviraline (GW-420867X) is a potent reverse transcriptase inhibitor that inhibits Human immunodeficiency virus 1 and has the potential to treat HIV infection. |
| In vivo | systemic exposure to Opaviraline decreases with increasing dose and displays time-variant pharmacokinetics, which suggests decreased absorption and/or increased clearance of Opaviraline. With an approximately 50-hour plasma half-life, Opaviraline is well-suited for once-daily dosing due to its relatively prolonged duration of action.[1] |
| Synonyms | HBY-1293, GW-867, GW867, GW-420867X, GW420867X |
| Molecular Weight | 280.29 |
| Formula | C14H17FN2O3 |
| Cas No. | 178040-94-3 |
| Smiles | C(OC(C)C)(=O)N1C=2C(NC(=O)[C@@H]1CC)=CC=C(F)C2 |
| Relative Density. | 1.204g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 10 mg/mL (35.68 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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