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Anti-Phospho-p40-phox (Thr154) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p40-phox (Thr154). Anti-Phospho-p40-phox (Thr154) Polyclonal Antibody can be used in IHC-P,IF(paraffin section),ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $218 | 7-10 days | |
100 μL | $317 | 7-10 days |
Description | Anti-Phospho-p40-phox (Thr154) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p40-phox (Thr154). Anti-Phospho-p40-phox (Thr154) Polyclonal Antibody can be used in IHC-P,IF(paraffin section),ELISA. |
Ig Type | IgG |
Reactivity | Human,Mouse |
Application | |
Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-300; ELISA: 1:5000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Appearance | Liquid |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Research Background | neutrophil cytosolic factor 4(NCF4) Homo sapiens The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding d |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | A synthesized phosphopeptide: human p40 phox around the phosphorylation site of Thr154. AA range:120-169 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Theoretical: 39 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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