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2-Amino-6-cyclopropylamino-9H-purine

🥰Excellent
Catalog No. T9462Cas No. 120503-69-7

2-Amino-6-cyclopropylamino-9H-purine,the key intermediate of abacavir was synthesized from ethyl cyanoacetate by nitrosation,cyclization with guanidine hydrochloride in the presence of EtONa and reduction to give 2,4,5-triamino-6-hydroxypyrimidine

2-Amino-6-cyclopropylamino-9H-purine

2-Amino-6-cyclopropylamino-9H-purine

🥰Excellent
Purity: 99.24%
Catalog No. T9462Cas No. 120503-69-7
2-Amino-6-cyclopropylamino-9H-purine,the key intermediate of abacavir was synthesized from ethyl cyanoacetate by nitrosation,cyclization with guanidine hydrochloride in the presence of EtONa and reduction to give 2,4,5-triamino-6-hydroxypyrimidine
Pack SizePriceAvailabilityQuantity
10 mg$31In Stock
25 mg$54In Stock
50 mg$81In Stock
100 mg$120In Stock
200 mg$181In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Purity:99.24%
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Product Introduction

Bioactivity
Description
2-Amino-6-cyclopropylamino-9H-purine,the key intermediate of abacavir was synthesized from ethyl cyanoacetate by nitrosation,cyclization with guanidine hydrochloride in the presence of EtONa and reduction to give 2,4,5-triamino-6-hydroxypyrimidine
Chemical Properties
Molecular Weight190.21
FormulaC8H10N6
Cas No.120503-69-7
SmilesNc1nc(NC2CC2)c2nc[nH]c2n1
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (289.15 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.2573 mL26.2867 mL52.5735 mL262.8674 mL
5 mM1.0515 mL5.2573 mL10.5147 mL52.5735 mL
10 mM0.5257 mL2.6287 mL5.2573 mL26.2867 mL
20 mM0.2629 mL1.3143 mL2.6287 mL13.1434 mL
50 mM0.1051 mL0.5257 mL1.0515 mL5.2573 mL
100 mM0.0526 mL0.2629 mL0.5257 mL2.6287 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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Keywords

2-Amino-6-cyclopropylamino-9H-purine2Amino6cyclopropylamino9Hpurine2 Amino 6 cyclopropylamino 9H purine
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