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SNX0723

🥰Excellent
Catalog No. T28824Cas No. 1073969-18-2
Alias SNX- 0723, SNX 0723

SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity. SNX0723 shows high binding affinity for HsHsp90 and PfHsp90 with Kis of 4.4 and 47 nM, respectively. SNX0723 inhibits liver-stage P. berghei ANKA parasites with the EC50 of 3.3 μM.

SNX0723

SNX0723

🥰Excellent
Purity: 99.85%
Catalog No. T28824Alias SNX- 0723, SNX 0723Cas No. 1073969-18-2
SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity. SNX0723 shows high binding affinity for HsHsp90 and PfHsp90 with Kis of 4.4 and 47 nM, respectively. SNX0723 inhibits liver-stage P. berghei ANKA parasites with the EC50 of 3.3 μM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$82In StockIn Stock
5 mg$198In StockIn Stock
10 mg$333In StockIn Stock
25 mg$538In StockIn Stock
50 mg$738In StockIn Stock
100 mg$990In StockIn Stock
500 mgPreferential-In Stock
1 mL x 10 mM (in DMSO)$217In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:99.85%
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Product Introduction

Bioactivity
Description
SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity. SNX0723 shows high binding affinity for HsHsp90 and PfHsp90 with Kis of 4.4 and 47 nM, respectively. SNX0723 inhibits liver-stage P. berghei ANKA parasites with the EC50 of 3.3 μM.
In vitro
SNX0723 inhibits P. falciparum Dd2 blood-stage parasites and P. berghei ANKA liver-stage parasites, EC50 are 7.4μM and 6.5μM, respectively[1].
SynonymsSNX- 0723, SNX 0723
Chemical Properties
Molecular Weight399.46
FormulaC22H26FN3O3
Cas No.1073969-18-2
SmilesCc1cn(c2CC(C)(C)CC(=O)c12)-c1cc(F)c(C(N)=O)c(N[C@H]2CCOC2)c1
Relative Density.1.37 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (150.2 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5034 mL12.5169 mL25.0338 mL125.1690 mL
5 mM0.5007 mL2.5034 mL5.0068 mL25.0338 mL
10 mM0.2503 mL1.2517 mL2.5034 mL12.5169 mL
20 mM0.1252 mL0.6258 mL1.2517 mL6.2584 mL
50 mM0.0501 mL0.2503 mL0.5007 mL2.5034 mL
100 mM0.0250 mL0.1252 mL0.2503 mL1.2517 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

SNX-0723SNX0723HSP90
Related Tags: buy SNX0723 | purchase SNX0723 | SNX0723 cost | order SNX0723 | SNX0723 chemical structure | SNX0723 in vitro | SNX0723 formula | SNX0723 molecular weight
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