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TargetMol | Tags Chromatin/Epigenetic
AMPK
(127)
Aurora Kinase
(80)
DNA Methyltransferase
(40)
Epigenetic Reader Domain
(342)
HDAC
(234)
HIF
(66)
HIF/HIF Prolyl-Hydroxylase
(77)
Histone Acetyltransferase
(48)
Histone Demethylase
(93)
Histone Methyltransferase
(223)
HuR
(4)
JAK
(191)
Methionine Adenosyltransferase (MAT)
(11)
MicroRNA
(13)
PAD
(10)
PARP
(156)
PKC
(173)
Pim
(41)
Sirtuin
(102)

Methionine Adenosyltransferase (MAT)

S-Adenosylmethionine synthetase, also known as methionine adenosyltransferase (MAT), is an enzyme that creates S-adenosylmethionine (also known as AdoMet, SAM or SAMe) by reacting methionine (a non-polar amino acid) and ATP (the basic currency of energy).

FilterHomeSignaling PathwaysChromatin/EpigeneticMethionine Adenosyltransferase (MAT)
AG-270
T90502201056-66-6In house
AG-270 is an allosteric and orally active inhibitor of MAT2A.
  • $112
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MAT2A-IN-9
T731402439277-80-0
MAT2A-IN-9, a 2-oxoquinazoline derivative, is a potent MAT2A (methionine adenylyltransferase 2A) inhibitor.MAT2A-IN-9 has antitumor activity for the treatment of lymphomas and solid tumors.
  • $74
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TargetMol | Inhibitor Sale
PF-9366
T519172882-78-1In house
PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor with an IC50 of 420 nM and a Kd of 170 nM.
  • $53
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FIDAS-3
T112841266684-01-8
FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities by effectively competing with S-adenosylmethionine (SAM) for MAT2A binding.
  • $44
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MAT2A inhibitor 2
T1195013299-99-5
MAT2A inhibitor 2 is an inhibitor of methionine adenosyltransferase 2A (MAT2A).
  • $47
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AGI-25696
T102592201066-35-3In house
AGI-25696 is an inhibitor of methionine adenosyltransferase 2A (MATA2). AGI-25696 blocks the growth of MTAP-deleted tumors in vivo and can be used for studies about the treatment of cancer.
  • $293
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MAT2A inhibitor 4
T92621391934-91-0
MAT2A inhibitor 4 is an inhibitor of the catalytic subunit of methionine S-adenosyltransferase-2, which is used in cancer research.
  • $48
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SCR-7952
T2010152798856-04-7
SCR-7952, a MAT2A inhibitor, is utilized in cancer research.
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10-14 weeks
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MAT2A-IN-10
T789462924825-23-8
MAT2A-IN-10 (Compound 28), an orally active inhibitor of MAT2A, exhibits an IC50 of 26 nM and is utilized in cancer research [1].
  • $1,370
8-10 weeks
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MAT2A-IN-12
T79350631897-75-1
MAT2A Allosteric Inhibitor 2 is a potent, selective inhibitor exhibiting an IC50 of 5 nM and demonstrates nanomolar efficacy (IC50 = 5 μM) in proliferation assays utilizing the MTAP - - cell line [1].
  • $1,520
8-10 weeks
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MAT2A-IN-11
T79349
MAT2A Allosteric Inhibitor 1, also known as Compound 5, is a selective inhibitor of methionine adenosyltransferase (MAT) demonstrating potent activity with an IC50 value of 6.8 nM [1].
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