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6-Chloro-2-fluoropurine

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Catalog No. T37065Cas No. 1651-29-2

6-Chloro-2-fluoropurine is a heterocyclic building block.1,2It has been used in the synthesis of purine nucleosides that inhibit cyclin-dependent kinases (CDKs)in vitro.16-Chloro-2-fluoropurine has also been used in the synthesis of purine nucleosides that are active against HIV-1 and hepatitis B virus (HBV)in vitro.2

6-Chloro-2-fluoropurine

6-Chloro-2-fluoropurine

😃Good
Catalog No. T37065Cas No. 1651-29-2
6-Chloro-2-fluoropurine is a heterocyclic building block.1,2It has been used in the synthesis of purine nucleosides that inhibit cyclin-dependent kinases (CDKs)in vitro.16-Chloro-2-fluoropurine has also been used in the synthesis of purine nucleosides that are active against HIV-1 and hepatitis B virus (HBV)in vitro.2
Pack SizePriceAvailabilityQuantity
250 mgTBD35 days
1 gTBD35 days
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Product Introduction

Bioactivity
Description
6-Chloro-2-fluoropurine is a heterocyclic building block.1,2It has been used in the synthesis of purine nucleosides that inhibit cyclin-dependent kinases (CDKs)in vitro.16-Chloro-2-fluoropurine has also been used in the synthesis of purine nucleosides that are active against HIV-1 and hepatitis B virus (HBV)in vitro.2
Chemical Properties
Molecular Weight172.55
FormulaC5H2ClFN4
Cas No.1651-29-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
Ethanol: 30 mg/mL (173.86 mM), Sonication is recommended.
DMSO: 30 mg/mL (173.86 mM), Sonication is recommended.
DMF: 30 mg/mL (173.86 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/DMSO/DMF
1mg5mg10mg50mg
1 mM5.7954 mL28.9771 mL57.9542 mL289.7711 mL
5 mM1.1591 mL5.7954 mL11.5908 mL57.9542 mL
10 mM0.5795 mL2.8977 mL5.7954 mL28.9771 mL
20 mM0.2898 mL1.4489 mL2.8977 mL14.4886 mL
50 mM0.1159 mL0.5795 mL1.1591 mL5.7954 mL
100 mM0.0580 mL0.2898 mL0.5795 mL2.8977 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

6-Chloro-2-fluoropurine6Chloro2fluoropurine6 Chloro 2 fluoropurine
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