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6-Chloro-2-fluoropurine

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Catalog No. T37065Cas No. 1651-29-2

6-Chloro-2-fluoropurine is a heterocyclic building block.1,2It has been used in the synthesis of purine nucleosides that inhibit cyclin-dependent kinases (CDKs)in vitro.16-Chloro-2-fluoropurine has also been used in the synthesis of purine nucleosides that are active against HIV-1 and hepatitis B virus (HBV)in vitro.2

6-Chloro-2-fluoropurine

6-Chloro-2-fluoropurine

😃Good
Catalog No. T37065Cas No. 1651-29-2
6-Chloro-2-fluoropurine is a heterocyclic building block.1,2It has been used in the synthesis of purine nucleosides that inhibit cyclin-dependent kinases (CDKs)in vitro.16-Chloro-2-fluoropurine has also been used in the synthesis of purine nucleosides that are active against HIV-1 and hepatitis B virus (HBV)in vitro.2
Pack SizePriceAvailabilityQuantity
250 mgTBD35 days
1 gTBD35 days
Bulk & Custom
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Product Introduction

Bioactivity
Description
6-Chloro-2-fluoropurine is a heterocyclic building block.1,2It has been used in the synthesis of purine nucleosides that inhibit cyclin-dependent kinases (CDKs)in vitro.16-Chloro-2-fluoropurine has also been used in the synthesis of purine nucleosides that are active against HIV-1 and hepatitis B virus (HBV)in vitro.2
Chemical Properties
Molecular Weight172.55
FormulaC5H2ClFN4
Cas No.1651-29-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
Ethanol: 30 mg/mL (173.86 mM), Sonication is recommended.
DMSO: 30 mg/mL (173.86 mM), Sonication is recommended.
DMF: 30 mg/mL (173.86 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/DMSO/DMF
1mg5mg10mg50mg
1 mM5.7954 mL28.9771 mL57.9542 mL289.7711 mL
5 mM1.1591 mL5.7954 mL11.5908 mL57.9542 mL
10 mM0.5795 mL2.8977 mL5.7954 mL28.9771 mL
20 mM0.2898 mL1.4489 mL2.8977 mL14.4886 mL
50 mM0.1159 mL0.5795 mL1.1591 mL5.7954 mL
100 mM0.0580 mL0.2898 mL0.5795 mL2.8977 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

6-Chloro-2-fluoropurine6Chloro2fluoropurine6 Chloro 2 fluoropurine
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