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Anti-Phospho-C-ABL1/2 (Tyr393/439) Polyclonal Antibody (Synonyms: p-C-ABL1/2 (Y393/439), p-C-ABL1/2 (Tyr393/439...)

Catalog No. TMAC-00049 Copy Product Info
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Anti-Phospho-C-ABL1/2 (Tyr393/439) Polyclonal Antibody is a Rabbit antibody targeting Phospho-C-ABL1/2 (Tyr393/439). Anti-Phospho-C-ABL1/2 (Tyr393/439) Polyclonal Antibody can be used in IF,IHC,WB.

Anti-Phospho-C-ABL1/2 (Tyr393/439) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-00049
Synonyms p-C-ABL1/2 (Y393/439), p-C-ABL1/2 (Tyr393/439), C-ABL1/2 (p-Y393/439), C-ABL1/2 (p-Tyr393/439)

Anti-Phospho-C-ABL1/2 (Tyr393/439) Polyclonal Antibody is a Rabbit antibody targeting Phospho-C-ABL1/2 (Tyr393/439). Anti-Phospho-C-ABL1/2 (Tyr393/439) Polyclonal Antibody can be used in IF,IHC,WB.

Anti-Phospho-C-ABL1/2
(Tyr393/439) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2167-10 days7-10 days
100 μL$3187-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-C-ABL1/2 (Tyr393/439) Polyclonal Antibody is a Rabbit antibody targeting Phospho-C-ABL1/2 (Tyr393/439). Anti-Phospho-C-ABL1/2 (Tyr393/439) Polyclonal Antibody can be used in IF,IHC,WB.
Synonymsp-C-ABL1/2 (Y393/439), p-C-ABL1/2 (Tyr393/439), C-ABL1/2 (p-Y393/439), C-ABL1/2 (p-Tyr393/439)
Ig Type
IgG
Reactivity
Human,Mouse
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ABL1/2(Phospho-Tyr393/439) Antibody TMAC-00049(left) or the same antibody preincubated with blocking peptide(right).
2. Immunofluorescence staining of methanol-fixed Hela cells using ABL1/2(phospho-Tyr393/439) Antibody TMAC-00049.
3. Western blot analysis of extracts from HL60 cells using ABL1/2(phospho-Tyr393/439) Antibody TMAC-00049 and the same antibody preincubated with blocking peptide.
verifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-100; IF: 1:100-200
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundRegulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 393/439 (D-T-Y(p)-T-A) derived from Human ABL1/2
Antigen Species
human
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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