Immobilized CD9 Protein-VLP, Human, Recombinant (Flag) (Cat#TMPY-07048) at 5 μg/mL (100 μL/well) can bind Anti-Human CD9 Monoclonal antibody, mouse IgG1, the EC50 is 3-10.5 ng/mL.

CD9 Protein-VLP, Human, Recombinant (Flag) is expressed in HEK293 Cells. The accession number is P21926.

Human

HEK293 Cells

TSPAN-29,TSPAN29,P24,MRP-1,MIC3,GIG2,DRAP-27,BTCC-1,BA2

A DNA sequence encoding the Human CD9-VLP (Full Length) (P21926) (Met1-Val228) was fused with a signal peptide at the N-terminus and a flag tag at the C-terminus.

Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -70℃ or lower. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD9 is a member of the transmembrane 4 superfamily, which is also known as the tetraspanin family. CD9 is a cell surface glycoprotein with 4 hydrophobic domains that are described as complex with integrins and other transmembrane 4 superfamily members. It is found expressed on the surface of the exosomes. The protein takes part in cellular signal transduction events and thus play a role in the regulation of cell development and activation, growth and motility. Besides, CD9 seems to be a key role in the egg-sperm fusion during the mammalian fertilization processes. CD9 is found on the membrane of the oocytes and also appears to intervene in maintaining the normal shape of oocyte microvilli.