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Anti-Phospho-Hck (Tyr411) Polyclonal Antibody (Synonyms: Tyrosine protein kinase HCK, p-Hck (Y411), p-Hck (Tyr...)
Catalog No. TMAB-01420 Copy Product Info
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Anti-Phospho-Hck (Tyr411) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Hck (Tyr411). Anti-Phospho-Hck (Tyr411) Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-Phospho-Hck (Tyr411) Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-01420
Synonyms Tyrosine protein kinase HCK, p-Hck (Y411), p-Hck (Tyr411), p59HCK/p60HCK, p59 HCK/p60 HCK, MGC18625, MGC 18625, JTK9, JTK 9, Hemopoietic cell kinase isoform p59 Hck, Hemopoietic cell kinase, Hck 1, Hck (p-Y411), Hck (p-Tyr411), HCK, Bmk
Anti-Phospho-Hck (Tyr411) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Hck (Tyr411). Anti-Phospho-Hck (Tyr411) Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-Phospho-Hck
(Tyr411) Polyclonal Antibody
(Tyr411) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-Phospho-Hck (Tyr411) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Hck (Tyr411). Anti-Phospho-Hck (Tyr411) Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| Synonyms | Tyrosine protein kinase HCK, p-Hck (Y411), p-Hck (Tyr411), p59HCK/p60HCK, p59 HCK/p60 HCK, MGC18625, MGC 18625, JTK9, JTK 9, Hemopoietic cell kinase isoform p59 Hck, Hemopoietic cell kinase, Hck 1, Hck (p-Y411), Hck (p-Tyr411), HCK, Bmk |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Chicken,Cow,Horse,Sheep) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (phospho-Hck (Tyr411)) Polyclonal Antibody, Unconjugated (TMAB-01420) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.  |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane. Cytoplasm. At least half of this isoform is found in the cytoplasm, some of this fraction is myristoylated and Membrane. Membrane > caveola. 20% of this isoform is associated with caveolae, this association depends on palmitoylation of cyteine at position 3. |
| Tissue Specificity | Detected in monocytes and neutrophils (at protein level). Expressed predominantly in cells of the myeloid and B-lymphoid lineages. Highly expressed in granulocytes. Detected in tonsil. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | HCK is a tyrosine kinase that is predominantly expressed in hemopoietic cell types. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. |
| Immunogen | KLH conjugated synthesised phosphopeptide: human Hck around the phosphorylation site of Tyr411 |
| Antigen Species | Human |
| Gene Name | HCK |
| Gene ID | |
| Protein Name | Tyrosine-protein kinase HCK |
| Uniprot ID | |
| Biology Area | Antiviral Signaling,Src Family |
| Function | May serve as part of a signaling pathway coupling the Fc receptor to the activation of the respiratory burst. May also contribute to neutrophil migration and may regulate the degranulation process of neutrophils. |
| Molecular Weight | Theoretical: 59 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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