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Anti-Phospho-Hck (Tyr411) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Hck (Tyr411). Anti-Phospho-Hck (Tyr411) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $222 | 7-10 days | |
100 μL | $374 | 7-10 days | |
200 μL | $529 | 7-10 days |
Description | Anti-Phospho-Hck (Tyr411) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Hck (Tyr411). Anti-Phospho-Hck (Tyr411) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
Alias | Tyrosine protein kinase HCK, p-Hck (Y411), p-Hck (Tyr411), p59HCK/p60HCK, p59 HCK/p60 HCK, MGC18625, MGC 18625, JTK9, JTK 9, Hemopoietic cell kinase isoform p59 Hck, Hemopoietic cell kinase, Hck 1, Hck (p-Y411), Hck (p-Tyr411), HCK, Bmk |
Ig Type | IgG |
Reactivity | Mouse (predicted:Human,Rat,Chicken,Cow,Horse,Sheep) |
Verified Activity | Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (phospho-Hck (Tyr411)) Polyclonal Antibody, Unconjugated (TMAB-01420) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining. |
Application | IHC-P,IHC-Fr,IF |
Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Membrane. Cytoplasm. At least half of this isoform is found in the cytoplasm, some of this fraction is myristoylated and Membrane. Membrane > caveola. 20% of this isoform is associated with caveolae, this association depends on palmitoylation of cyteine at position 3. |
Construction | Hybridoma Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | HCK is a tyrosine kinase that is predominantly expressed in hemopoietic cell types. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. |
Immunogen | KLH conjugated synthesised phosphopeptide: human Hck around the phosphorylation site of Tyr411 |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | Antiviral Signaling,Src Family |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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