Shopping Cart
- Remove All
- Your shopping cart is currently empty
Anti-FGF-23 Polyclonal Antibody is a Rabbit antibody targeting FGF-23. Anti-FGF-23 Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $222 | 7-10 days | |
100 μL | $373 | 7-10 days | |
200 μL | $527 | 7-10 days |
Description | Anti-FGF-23 Polyclonal Antibody is a Rabbit antibody targeting FGF-23. Anti-FGF-23 Polyclonal Antibody can be used in WB. |
Synonyms | Fibroblast growth factor 23, FGF-23, Fgf23 |
Ig Type | IgG |
Reactivity | Human,Rat (predicted:Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep,GuineaPig) |
Verified Activity | 1. Sample: bone (rat) lysate at 40 μg Primary: Anti-MRPL32 (TMAB-00671) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 27 kDa Observed band size: 27 kDa 2. Sample: Lane 1: Bone (Rat) Lysate at 40 μg Lane 2: Cerebrum (Rat) Lysate at 40 μg Primary: Anti-FGF23 (TMAB-00671) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 30/32 kDa Observed band size: 30 kDa |
Application | |
Recommended Dose | WB: 1:500-2000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Secreted. Note=Secretion is dependent on O-glycosylation. |
Tissue Specificity | Expressed in osteogenic cells particularly during phases of active bone remodeling. In adult trabecular bone, expressed in osteocytes and flattened bone-lining cells (inactive osteoblasts). |
Construction | Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Concentration | 1 mg/mL |
Research Background | This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013] |
Immunogen | KLH conjugated synthetic peptide: human Fibroblast growth factor 23 |
Antigen Species | Human |
Gene Name | FGF23 |
Gene ID | |
Protein Name | Fibroblast growth factor 23 |
Uniprot ID | |
Function | Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL. Acts directly on the parathyroid to decrease PTH secretion. Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. |
Molecular Weight | Theoretical: 27 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.