Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-ICAM-1/CD54 Antibody (2I549)

😃Good
Catalog No. TMAY-03294
Alias P3.58, intercellular adhesion molecule 1, ICAM-1, CD54, BB2

Anti-ICAM-1/CD54 Antibody (2I549) is a Rabbit antibody targeting ICAM-1/CD54. Anti-ICAM-1/CD54 Antibody (2I549) can be used in ELISA,ELISA(Cap),IHC-P.

Anti-ICAM-1/CD54 Antibody (2I549)

Anti-ICAM-1/CD54 Antibody (2I549)

😃Good
Catalog No. TMAY-03294Alias P3.58, intercellular adhesion molecule 1, ICAM-1, CD54, BB2
Anti-ICAM-1/CD54 Antibody (2I549) is a Rabbit antibody targeting ICAM-1/CD54. Anti-ICAM-1/CD54 Antibody (2I549) can be used in ELISA,ELISA(Cap),IHC-P.
Pack SizePriceAvailabilityQuantity
20 μL$92 7-10 days
100 μL$294 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Antibody Type: Rabbit Monoclonal

Application: ELISA, ELISA(Cap), IHC-P

Reactivity: Mouse
AliasP3.58, intercellular adhesion molecule 1, ICAM-1, CD54, BB2
Ig Type
Rabbit IgG
Clone
2I549
Reactivity
Mouse
Verified Activity
1. Immunochemical staining of mouse ICAM1 in mouse kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to blood vessel.
2. Immunochemical staining of mouse ICAM1 in mouse brain with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). The image showing positive staining of choroid plexus.
Application
ELISA,ELISA(Cap),IHC-P
Recommended Dose
ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500; ELISA(Cap): 1:250-1:2000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD54 / ICAM1 (rM CD54 / ICAM1; TMPY-01349; NP_034623.1; Met 1-Asn 485).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundIntercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and animal models of atherosclerosis. Additionally, ICAM-1 has been implicated in the progression of autoimmune diseases. ICAM-1 is a ligand for LFA-1(integrin). When activated, leukocytes bind to endothelial cells via ICAM-1/LFA-1 interaction and then transmigrate into tissues. Presence with heavy glycosylation and other structural characteristics, ICAM-1 possesses binding sites for some immune-associated ligands and serves as the binding site for entry of the major group of human Rhinovirus (HRV) into various cell types. ICAM-1 also becomes known for its affinity for Plasmodium falciparum-infected erythrocytes (PFIE), providing more of a role in infectious disease. Previous studies have shown that ICAM-1 is involved in inflammatory reactions and that a defect in ICAM-1 gene inhibits allergic contact hypersensitivity.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Mouse CD54 / ICAM1 protein (TMPY-01349)
Antigen Species
Mouse
Biology Area
Neuroinflammation
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Anti-ICAM-1/CD54 Antibody (2I549) | purchase Anti-ICAM-1/CD54 Antibody (2I549) | Anti-ICAM-1/CD54 Antibody (2I549) cost | order Anti-ICAM-1/CD54 Antibody (2I549)