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Anti-ICAM-1/CD54 Antibody (2I549) (Synonyms: P3.58, intercellular adhesion molecule 1, ICAM-1, CD54, BB2)
Catalog No. TMAY-03294 Copy Product Info
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Anti-ICAM-1/CD54 Antibody (2I549) is a Rabbit antibody targeting ICAM-1/CD54. Anti-ICAM-1/CD54 Antibody (2I549) can be used in ELISA,ELISA(Cap),IHC-P.
Anti-ICAM-1/CD54 Antibody (2I549)
Copy Product Info🥰Excellent
Catalog No. TMAY-03294
Synonyms P3.58, intercellular adhesion molecule 1, ICAM-1, CD54, BB2
Anti-ICAM-1/CD54 Antibody (2I549) is a Rabbit antibody targeting ICAM-1/CD54. Anti-ICAM-1/CD54 Antibody (2I549) can be used in ELISA,ELISA(Cap),IHC-P.
Anti-ICAM-1/CD54 Antibody
(2I549)
(2I549)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 μL | $92 | 7-10 days | 7-10 days | |
| 100 μL | $294 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Related Conjugates and Formulations
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| Description | Anti-ICAM-1/CD54 Antibody (2I549) is a Rabbit antibody targeting ICAM-1/CD54. Anti-ICAM-1/CD54 Antibody (2I549) can be used in ELISA,ELISA(Cap),IHC-P. |
| Synonyms | P3.58, intercellular adhesion molecule 1, ICAM-1, CD54, BB2 |
| Ig Type | Rabbit IgG |
| Clone | 2I549 |
| Reactivity | Mouse |
| Specificity | Mouse ICAM-1/CD54 No cross-reactivity in ELISA with Human ICAM1 Human CD31 Human ICAM3 Human ICAM2 Mouse VCAM1 |
| Verified Activity | 1. Immunochemical staining of mouse ICAM1 in mouse kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to blood vessel. 2. Immunochemical staining of mouse ICAM1 in mouse brain with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). The image showing positive staining of choroid plexus. |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500; ELISA(Cap): 1:250-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD54 / ICAM1 (rM CD54 / ICAM1; TMPY-01349; NP_034623.1; Met 1-Asn 485). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and animal models of atherosclerosis. Additionally, ICAM-1 has been implicated in the progression of autoimmune diseases. ICAM-1 is a ligand for LFA-1(integrin). When activated, leukocytes bind to endothelial cells via ICAM-1/LFA-1 interaction and then transmigrate into tissues. Presence with heavy glycosylation and other structural characteristics, ICAM-1 possesses binding sites for some immune-associated ligands and serves as the binding site for entry of the major group of human Rhinovirus (HRV) into various cell types. ICAM-1 also becomes known for its affinity for Plasmodium falciparum-infected erythrocytes (PFIE), providing more of a role in infectious disease. Previous studies have shown that ICAM-1 is involved in inflammatory reactions and that a defect in ICAM-1 gene inhibits allergic contact hypersensitivity. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse CD54 / ICAM1 protein (TMPY-01349) |
| Antigen Species | Mouse |
| Biology Area | Neuroinflammation |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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