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Prednisolone valerate acetate
🥰Excellent
Catalog No. T20734Cas No. 72064-79-0
Alias Lidomex, Acepreval
Prednisolone valerate acetate (Lidomex) is a corticosteroid hormone and prodrug with anti-inflammatory and immunosuppressive effects, which is converted to the active form of Prednisolone upon administration and acts by targeting the glucocorticoid receptor.
Prednisolone valerate acetate
🥰Excellent
Purity: 99.93%
Catalog No. T20734Alias Lidomex, AceprevalCas No. 72064-79-0
Prednisolone valerate acetate (Lidomex) is a corticosteroid hormone and prodrug with anti-inflammatory and immunosuppressive effects, which is converted to the active form of Prednisolone upon administration and acts by targeting the glucocorticoid receptor.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $441 | In Stock | |
| 5 mg | $987 | In Stock | |
| 10 mg | $1,390 | In Stock | |
| 25 mg | $1,980 | In Stock | |
| 50 mg | $2,780 | In Stock |
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Purity:99.93%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Prednisolone valerate acetate (Lidomex) is a corticosteroid hormone and prodrug with anti-inflammatory and immunosuppressive effects, which is converted to the active form of Prednisolone upon administration and acts by targeting the glucocorticoid receptor. |
| In vivo | Prednisolone valerate acetate (PVA) was administered to mice via s.c. injection at 0.03–1 mg/kg, with immune responses assessed at 24–48 h and 5–7 d for antibody production. PVA reduced spleen weight and splenic nucleated cell counts, suppressed hemolytic plaque-forming cell (PFC) formation, delayed-type hypersensitivity (DTH), and ConA-induced splenocyte proliferation. Notably, PVA inhibited LPS-induced splenocyte response and IgM antibody production at lower doses than hydrocortisone 17-butyrate (HB), indicating higher potency. Unlike HB and betamethasone 17-valerate (BV), PVA had no effect on PHA-P response. Its suppression of host defense against experimental E. coli infection was weaker than that of HB and BV. [1] |
| Alias | Lidomex, Acepreval |
| Molecular Weight | 486.6 |
| Formula | C28H38O7 |
| Cas No. | 72064-79-0 |
| Smiles | C(COC(C)=O)(=O)[C@]1(OC(CCCC)=O)[C@]2(C)[C@@](CC1)([C@]3([C@]([C@@H](O)C2)([C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H])[H] |
| Relative Density. | 1.22 g/cm3 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||
| Solubility Information | DMSO: 4 mg/mL (8.22 mM), Sonication is recommended. | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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