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Anti-Thrombin Receptor Polyclonal Antibody
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Catalog No. TMAB-01833
Alias TR, PAR-1, PAR1, HTR, coagulation factor II (thrombin) receptor, CF2R
Anti-Thrombin Receptor Polyclonal Antibody is a Rabbit antibody targeting Thrombin Receptor. Anti-Thrombin Receptor Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Anti-Thrombin Receptor Polyclonal Antibody
Anti-Thrombin Receptor Polyclonal Antibody
😃Good
Catalog No. TMAB-01833Alias TR, PAR-1, PAR1, HTR, coagulation factor II (thrombin) receptor, CF2R
Anti-Thrombin Receptor Polyclonal Antibody is a Rabbit antibody targeting Thrombin Receptor. Anti-Thrombin Receptor Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Thrombin Receptor Polyclonal Antibody is a Rabbit antibody targeting Thrombin Receptor. Anti-Thrombin Receptor Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | TR, PAR-1, PAR1, HTR, coagulation factor II (thrombin) receptor, CF2R |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. 25 μg total protein per Lane of various lysates probed with PAR1 polyclonal antibody, unconjugated (TMAB-01833) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min. 2. Paraformaldehyde-fixed, paraffin embedded Rat Testicles; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with PAR1 Polyclonal Antibody, Unconjugated (TMAB-01833) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded Rat Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with PAR1 Polyclonal Antibody, Unconjugated (TMAB-01833) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 4. Paraformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with PAR1 Polyclonal Antibody, Unconjugated (TMAB-01833) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 5. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with PAR1 Polyclonal Antibody, Unconjugated (TMAB-01833) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 6. Paraformaldehyde-fixed, paraffin embedded Human Placenta; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with PAR1 Polyclonal Antibody, Unconjugated (TMAB-01833) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 7. Paraformaldehyde-fixed, paraffin embedded Human Pancreatic Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with PAR1 Polyclonal Antibody, Unconjugated (TMAB-01833) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.        |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Platelets and vascular endothelial cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human PAR1 |
| Antigen Species | Human |
| Gene Name | F2R |
| Gene ID | |
| Protein Name | Proteinase-activated receptor 1 |
| Uniprot ID | |
| Function | High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development. |
| Molecular Weight | Theoretical: 42 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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