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AP-III-a4 hydrochloride

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Catalog No. T6759LCas No. 2070014-95-6
Alias ENOblock hydrochloride, AP-III-a4 hydrochloride (1177827-73-4 free base)

AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor with non-substrate analogs.AP-III-a4 hydrochloride inhibits metastasis of cancer cells in vivo and affects glucose homeostasis and can be used in bioassays.

AP-III-a4 hydrochloride
Other Forms of AP-III-a4 hydrochloride:
AP-III-a4T67591177827-73-4
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AP-III-a4 hydrochloride

😃Good
Catalog No. T6759LAlias ENOblock hydrochloride, AP-III-a4 hydrochloride (1177827-73-4 free base)Cas No. 2070014-95-6
AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor with non-substrate analogs.AP-III-a4 hydrochloride inhibits metastasis of cancer cells in vivo and affects glucose homeostasis and can be used in bioassays.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$98BackorderBackorder
5 mg$188BackorderBackorder
10 mg$302BackorderBackorder
25 mg$619BackorderBackorder
50 mg$873BackorderBackorder
100 mgInquiryBackorderBackorder
200 mgInquiryBackorderBackorder
1 mL x 10 mM (in DMSO)$260BackorderBackorder
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor with non-substrate analogs.AP-III-a4 hydrochloride inhibits metastasis of cancer cells in vivo and affects glucose homeostasis and can be used in bioassays.
SynonymsENOblock hydrochloride, AP-III-a4 hydrochloride (1177827-73-4 free base)
Chemical Properties
Molecular Weight631.18
FormulaC31H44ClFN8O3
Cas No.2070014-95-6
SmilesO=C(CC1=CC=C(NC2=NC(NCC3CCCCC3)=NC(NCC4=CC=C(C=C4)F)=N2)C=C1)NCCOCCOCCN.Cl
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 40 mg/mL (63.37 mM), Sonication is recommended.
H2O: 8 mg/mL (12.67 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM1.5843 mL7.9217 mL15.8433 mL79.2167 mL
5 mM0.3169 mL1.5843 mL3.1687 mL15.8433 mL
10 mM0.1584 mL0.7922 mL1.5843 mL7.9217 mL
DMSO
1mg5mg10mg50mg
20 mM0.0792 mL0.3961 mL0.7922 mL3.9608 mL
50 mM0.0317 mL0.1584 mL0.3169 mL1.5843 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

ENOblock HydrochlorideAP-III-a-4 hydrochloride (1177827-73-4 free base)APIIIa4 hydrochloride (1177827734 free base)AP-III-a4 hydrochlorideAP-III-a4 HydrochlorideAP III a4 hydrochloride (1177827 73 4 free base)1177827-73-4 free base1177827-73-4
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