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Propylthiouracil

Name: Propylthiouracil
Brand: TargetMol
SKU: T1309
Rating: 4.5 (1 reviews)

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Catalog No. T1309Cas No. 51-52-5

Alias Pseudocapsaicin, NSC 70461, NSC 6498, 6-Propyl-2-thiouracil, 6-n-Propylthiouracil

Propylthiouracil (6-n-Propylthiouracil) is a thyroid peroxidase inhibitor and also a 5' -deiodinase inhibitor.

Propylthiouracil

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Purity: 99.24%

Catalog No. T1309Alias Pseudocapsaicin, NSC 70461, NSC 6498, 6-Propyl-2-thiouracil, 6-n-PropylthiouracilCas No. 51-52-5

Propylthiouracil (6-n-Propylthiouracil) is a thyroid peroxidase inhibitor and also a 5' -deiodinase inhibitor.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.24%

Appearance:Solid

Color:White

Resource Download

COA LCMS HPLC HNMR

Product Introduction

Bioactivity

Description	Propylthiouracil (6-n-Propylthiouracil) is a thyroid peroxidase inhibitor and also a 5' -deiodinase inhibitor.
Synonyms	Pseudocapsaicin, NSC 70461, NSC 6498, 6-Propyl-2-thiouracil, 6-n-Propylthiouracil

Chemical Properties

Molecular Weight	170.23
Formula	C₇H₁₀N₂OS
Cas No.	51-52-5
Smiles	CCCC1=CC(O)=NC(S)=N1
Relative Density.	1.1880 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 65 mg/mL (381.84 mM), Sonication is recommended.

Ethanol: 16 mg/mL (93.99 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (11.75 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	5.8744 mL	29.3720 mL	58.7441 mL	293.7203 mL
5 mM	1.1749 mL	5.8744 mL	11.7488 mL	58.7441 mL
10 mM	0.5874 mL	2.9372 mL	5.8744 mL	29.3720 mL
20 mM	0.2937 mL	1.4686 mL	2.9372 mL	14.6860 mL
50 mM	0.1175 mL	0.5874 mL	1.1749 mL	5.8744 mL

DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0587 mL	0.2937 mL	0.5874 mL	2.9372 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc