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Adoprazine

Name: Adoprazine
Brand: TargetMol
SKU: T10249
Price: 58 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T10249Cas No. 222551-17-9

Alias SLV313

Adoprazine (SLV313) is a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties.

Adoprazine

🥰Excellent

Purity: 99.83%

Catalog No. T10249Alias SLV313Cas No. 222551-17-9

Adoprazine (SLV313) is a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$58	In Stock	In Stock
5 mg	$139	In Stock	In Stock
10 mg	$228	In Stock	In Stock
25 mg	$403	In Stock	In Stock
50 mg	$645	In Stock	In Stock
100 mg	$868	-	In Stock
1 mL x 10 mM (in DMSO)	$153	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.83%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Adoprazine (SLV313) is a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties.
Targets&IC50	D4 Receptor:8.0 (pKi), D2 Receptor:9.3 (pA2), 5-HT1A receptor:9 (pEC50), 5-HT7 receptor:7.2 (pKi), D3 receptor:8.9 (pA2), 5-HT1A receptor:9.1 (pKi), D2 Receptor:8.4 (pKi), D3 receptor:8.4 (pKi)
Synonyms	SLV313

Chemical Properties

Molecular Weight	405.46
Formula	C₂₄H₂₄FN₃O₂
Cas No.	222551-17-9
Smiles	Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2cccc3OCCOc23)c1
Relative Density.	1.256 g/cm3
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (110.99 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2.5 mg/mL (6.17 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4663 mL	12.3317 mL	24.6633 mL	123.3167 mL
5 mM	0.4933 mL	2.4663 mL	4.9327 mL	24.6633 mL
10 mM	0.2466 mL	1.2332 mL	2.4663 mL	12.3317 mL
20 mM	0.1233 mL	0.6166 mL	1.2332 mL	6.1658 mL
50 mM	0.0493 mL	0.2466 mL	0.4933 mL	2.4663 mL
100 mM	0.0247 mL	0.1233 mL	0.2466 mL	1.2332 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc