Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(E)-TCO-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Description | (E)-TCO-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | (E)-TCO-PEG4-NHS ester |
Molecular Weight | 514.572 |
Formula | C24H38N2O10 |
CAS No. | 1621096-79-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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(E)-TCO-PEG4-NHS ester 1621096-79-4 (E)-TCO-PEG-4-NHS ester TCO-PEG4-NHS ester (E) TCO PEG4 NHS ester (E)TCOPEG4NHS ester inhibitor inhibit