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Anti-Phospho-RPS6KA1 (S380) Antibody (2P405)
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Catalog No. TMAC-03262
Anti-Phospho-RPS6KA1 (S380) Antibody (2P405) is a Rabbit antibody targeting Phospho-RPS6KA1 (S380). Anti-Phospho-RPS6KA1 (S380) Antibody (2P405) can be used in WB,ICC/IF,IP.
Anti-Phospho-RPS6KA1 (S380) Antibody (2P405)
Anti-Phospho-RPS6KA1 (S380) Antibody (2P405)
😃Good
Catalog No. TMAC-03262
Anti-Phospho-RPS6KA1 (S380) Antibody (2P405) is a Rabbit antibody targeting Phospho-RPS6KA1 (S380). Anti-Phospho-RPS6KA1 (S380) Antibody (2P405) can be used in WB,ICC/IF,IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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| Description | Anti-Phospho-RPS6KA1 (S380) Antibody (2P405) is a Rabbit antibody targeting Phospho-RPS6KA1 (S380). Anti-Phospho-RPS6KA1 (S380) Antibody (2P405) can be used in WB,ICC/IF,IP. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:1000-5000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The family of ribosomal S6 kinases (Rsks), designated Rsk-1, Rsk-2 and Rsk-3, are important signaling intermediates that mediate responses to a broad range of ligand-activated receptor tyrosine kinases. It has been established that Rsk-3 is not activated by MAP kinase in vitro, unlike Rsk-1 and Rsk-2. A unique feature common to the three members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. The Rsk family amino-terminal kinase domain is phosphorylated on Ser 227 by 3-phosphoinositide-dependent protein kinase-1 (PDK1), which increases the kinase activity of Rsk. In the carboxy-terminal kinase domain, Rsk-1 and Rsk-2 are autophosphorylated on Ser 380 and Ser 386, respectively, which mediates the docking of PDK1 to Rsk in order to promote phosphorylation of substrates, such as histone H3. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human RSK1 around the phosphorylation site of Ser380 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 90 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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