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Anti-Phospho-RPS6KA1 (Ser380) Antibody (2P405)

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Catalog No. TMAC-03262
Alias S6K-alpha-1, S6K alpha 1, RSK1p90, RSK1, RSK 1 p90, RSK 1, RSK, RPS6KA1 (p-Ser380), RPS6KA1 (p-S380), rps6ka, RPS6K1 alpha, Ribosomal S6 kinase 1, Ribosomal protein S6 kinase polypeptide 1, Ribosomal protein S6 kinase alpha 1, Ribosomal protein S6 kinase 90kD polypeptide 1, ribosomal protein S6 kinase, p-RPS6KA1 (Ser380), p-RPS6KA1 (S380), pp90RSK1, polypeptide 1, Phospho-RPS6KA1 (S380), p90S6K, p90RSK1, p90 RSK1, OTTHUMP00000004113, Mitogen-activated protein kinase-activated protein kinase 1A, MGC79981, MAPKAPK-1a, MAPKAPK1A, MAPKAP kinase 1a, MAP kinase activated protein kinase 1a, KS6A1_HUMAN, HU1, HU 1, EC 2.7.11.1, dJ590P13.1, 90kD, 90 kDa ribosomal protein S6 kinase 1

Anti-Phospho-RPS6KA1 (Ser380) Antibody (2P405) is a Rabbit antibody targeting Phospho-RPS6KA1 (Ser380). Anti-Phospho-RPS6KA1 (Ser380) Antibody (2P405) can be used in ICC/IF,IP,WB.

Anti-Phospho-RPS6KA1 (Ser380) Antibody (2P405)

Anti-Phospho-RPS6KA1 (Ser380) Antibody (2P405)

😃Good
Catalog No. TMAC-03262Alias S6K-alpha-1, S6K alpha 1, RSK1p90, RSK1, RSK 1 p90, RSK 1, RSK, RPS6KA1 (p-Ser380), RPS6KA1 (p-S380), rps6ka, RPS6K1 alpha, Ribosomal S6 kinase 1, Ribosomal protein S6 kinase polypeptide 1, Ribosomal protein S6 kinase alpha 1, Ribosomal protein S6 kinase 90kD polypeptide 1, ribosomal protein S6 kinase, p-RPS6KA1 (Ser380), p-RPS6KA1 (S380), pp90RSK1, polypeptide 1, Phospho-RPS6KA1 (S380), p90S6K, p90RSK1, p90 RSK1, OTTHUMP00000004113, Mitogen-activated protein kinase-activated protein kinase 1A, MGC79981, MAPKAPK-1a, MAPKAPK1A, MAPKAP kinase 1a, MAP kinase activated protein kinase 1a, KS6A1_HUMAN, HU1, HU 1, EC 2.7.11.1, dJ590P13.1, 90kD, 90 kDa ribosomal protein S6 kinase 1
Anti-Phospho-RPS6KA1 (Ser380) Antibody (2P405) is a Rabbit antibody targeting Phospho-RPS6KA1 (Ser380). Anti-Phospho-RPS6KA1 (Ser380) Antibody (2P405) can be used in ICC/IF,IP,WB.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-RPS6KA1 (Ser380) Antibody (2P405) is a Rabbit antibody targeting Phospho-RPS6KA1 (Ser380). Anti-Phospho-RPS6KA1 (Ser380) Antibody (2P405) can be used in ICC/IF,IP,WB.
SynonymsS6K-alpha-1, S6K alpha 1, RSK1p90, RSK1, RSK 1 p90, RSK 1, RSK, RPS6KA1 (p-Ser380), RPS6KA1 (p-S380), rps6ka, RPS6K1 alpha, Ribosomal S6 kinase 1, Ribosomal protein S6 kinase polypeptide 1, Ribosomal protein S6 kinase alpha 1, Ribosomal protein S6 kinase 90kD polypeptide 1, ribosomal protein S6 kinase, p-RPS6KA1 (Ser380), p-RPS6KA1 (S380), pp90RSK1, polypeptide 1, Phospho-RPS6KA1 (S380), p90S6K, p90RSK1, p90 RSK1, OTTHUMP00000004113, Mitogen-activated protein kinase-activated protein kinase 1A, MGC79981, MAPKAPK-1a, MAPKAPK1A, MAPKAP kinase 1a, MAP kinase activated protein kinase 1a, KS6A1_HUMAN, HU1, HU 1, EC 2.7.11.1, dJ590P13.1, 90kD, 90 kDa ribosomal protein S6 kinase 1
Ig Type
IgG
Clone
2P405
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of Phospho-RSK1 (S380) on A431 cell lysates using anti-Phospho-RSK1 (S380) antibody at 1/1,000 dilution.
2. ICC staining Phospho-RSK1 (S380) in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining Phospho-RSK1 (S380) in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining Phospho-RSK1 (S380) in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
ICC/IF
IP
WB
Recommended Dose
WB: 1:1000-5000; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe family of ribosomal S6 kinases (Rsks), designated Rsk-1, Rsk-2 and Rsk-3, are important signaling intermediates that mediate responses to a broad range of ligand-activated receptor tyrosine kinases. It has been established that Rsk-3 is not activated by MAP kinase in vitro, unlike Rsk-1 and Rsk-2. A unique feature common to the three members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. The Rsk family amino-terminal kinase domain is phosphorylated on Ser 227 by 3-phosphoinositide-dependent protein kinase-1 (PDK1), which increases the kinase activity of Rsk. In the carboxy-terminal kinase domain, Rsk-1 and Rsk-2 are autophosphorylated on Ser 380 and Ser 386, respectively, which mediates the docking of PDK1 to Rsk in order to promote phosphorylation of substrates, such as histone H3.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human RSK1 around the phosphorylation site of Ser380
Antigen Species
human
Uniprot ID
Q15418
Chemical Properties
Molecular WeightTheoretical: 90 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Keywords

RPS6KA1 (pSer380)RPS6KA1 (pS380)RPS6KA1 (phospho-Ser380)RPS6KA1 (phospho-S380)pRPS6KA1 (Ser380)pRPS6KA1 (S380)
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