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Anti-EGFR Antibody-PE (5D853)
🥰Excellent
Catalog No. TMAY-00022P
Anti-EGFR Antibody-PE (5D853) is a PE-conjugated Mouse antibody targeting EGFR. Anti-EGFR Antibody-PE (5D853) can be used in FCM.
Anti-EGFR Antibody-PE (5D853)
Anti-EGFR Antibody-PE (5D853)
🥰Excellent
Catalog No. TMAY-00022P
Anti-EGFR Antibody-PE (5D853) is a PE-conjugated Mouse antibody targeting EGFR. Anti-EGFR Antibody-PE (5D853) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-EGFR Antibody-PE (5D853) is a PE-conjugated Mouse antibody targeting EGFR. Anti-EGFR Antibody-PE (5D853) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 5D853 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of EGFR expression on human A431 cells. |
| Application | FCM |
| Recommended Dose | 2 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This product is a recombinant monoclonal antibody expressed from HEK293 cells. Then conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | PE |
| Others Formats | Unconjugated/APC/FITC/Biotin |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Human EGFR / HER1 / ErbB1 protein (TMPY-00742) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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