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Anti-EGFR Antibody-PE (5D853)
(Synonyms: PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor) Copy Product Info
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Synonyms: PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor
Catalog No. TMAY-00022P Copy Product Info
🥰Excellent
Anti-EGFR Antibody-PE (5D853) is a PE-conjugated Mouse antibody targeting EGFR. Anti-EGFR Antibody-PE (5D853) can be used in FCM.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 T | $105 | 7-10 days | 7-10 days | |
| 100 T | $328 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
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Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-EGFR Antibody-PE (5D853) is a PE-conjugated Mouse antibody targeting EGFR. Anti-EGFR Antibody-PE (5D853) can be used in FCM. |
| Synonyms | PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor |
| Ig Type | Mouse IgG1 |
| Clone | 5D853 |
| Reactivity | Human |
| Specificity | Human EGFR |
| Application | |
| Recommended Dose | 2 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This product is a recombinant monoclonal antibody expressed from HEK293 cells. Then conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | PE |
| Others Formats | Unconjugated/APC/FITC/Biotin |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Protein: Human EGFR / HER1 / ErbB1 protein (TMPY-00742) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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