Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PRMT6-IN-3 is a selective PRMT6 inhibitor with an IC50 value of 192 nM.PRMT6-IN-3 has anticancer activity and induces apoptosis in cancer cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 83.00 | |
5 mg | In stock | $ 198.00 | |
10 mg | In stock | $ 295.00 | |
25 mg | In stock | $ 495.00 | |
50 mg | In stock | $ 719.00 | |
100 mg | In stock | $ 987.00 | |
500 mg | In stock | $ 1,980.00 |
Description | PRMT6-IN-3 is a selective PRMT6 inhibitor with an IC50 value of 192 nM.PRMT6-IN-3 has anticancer activity and induces apoptosis in cancer cells. |
Targets&IC50 | PRMT6:192 nM |
In vitro |
PRMT6-IN-3 (compound 25) (0-40 μM; 72 h) significantly induces apoptosis of cancer cells in a dose-dependent manner. Among them, a concentration of 40 μM could induce apoptosis in 43.44% and 35.08% of HCC827 and MDA-MB-435 cells, respectively.[1] PRMT6-IN-3 (80 μM; 3-7 days) has anti-proliferative activity against HCC827 and MDA-MB-435 cells.[1] |
Molecular Weight | 374.5 |
Formula | C19H26N4O2S |
CAS No. | 2890765-10-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PRMT6-IN-3 2890765-10-1 Apoptosis Chromatin/Epigenetic Histone Methyltransferase inhibitor inhibit