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PI3Kα-IN-16 (Z86) is a recently developed inhibitor of PI3Kα, displaying an IC 50 of 4.28 μM. With potent efficacy, it inhibits the growth and migration of CRCs mediated by PI3K. Additionally, PI3Kα-IN-16 also suppresses the Wnt signaling pathway [1].

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 mg | Inquiry | 3-6 months | 3-6 months | |
| 50 mg | Inquiry | 3-6 months | 3-6 months | |
| 100 mg | Inquiry | 3-6 months | 3-6 months |
| Description | PI3Kα-IN-16 (Z86) is a recently developed inhibitor of PI3Kα, displaying an IC 50 of 4.28 μM. With potent efficacy, it inhibits the growth and migration of CRCs mediated by PI3K. Additionally, PI3Kα-IN-16 also suppresses the Wnt signaling pathway [1]. |
| Molecular Weight | 408.49 |
| Formula | C27H24N2O2 |
| Cas No. | 1448711-61-2 |
| Smiles | C(C)N1C=2C(C=3C1=CC=CC3)=CC(C(OC(C)C)=O)=NC2C=4C5=C(C=CC4)C=CC=C5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
| Size | Quantity | Unit Price | Amount | Operation |
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