Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-Stabilin-2 Polyclonal Antibody

😃Good
Catalog No. TMAB-01778
Alias STAB-2, STAB 2, link domain-containing scavenger receptor 2, laminin-type EGF-like and link domain-containing scavenger receptor 2, Hyaluronan receptor for endocytosis, HARE, FEX2, FELL, FEEL-2, FEEL2, Fasciclin, FAS1 EGF-like and X-link domain-containing adhesion molecule 2, EGF-like, 190 kDa hyaluronan receptor for endocytosis, 190 kDa form stabilin-2

Anti-Stabilin-2 Polyclonal Antibody is a Rabbit antibody targeting Stabilin-2. Anti-Stabilin-2 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.

Anti-Stabilin-2 Polyclonal Antibody

Anti-Stabilin-2 Polyclonal Antibody

😃Good
Catalog No. TMAB-01778Alias STAB-2, STAB 2, link domain-containing scavenger receptor 2, laminin-type EGF-like and link domain-containing scavenger receptor 2, Hyaluronan receptor for endocytosis, HARE, FEX2, FELL, FEEL-2, FEEL2, Fasciclin, FAS1 EGF-like and X-link domain-containing adhesion molecule 2, EGF-like, 190 kDa hyaluronan receptor for endocytosis, 190 kDa form stabilin-2
Anti-Stabilin-2 Polyclonal Antibody is a Rabbit antibody targeting Stabilin-2. Anti-Stabilin-2 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Pack SizePriceAvailabilityQuantity
50 μL$2207-10 days
100 μL$3737-10 days
200 μL$5297-10 days
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Product Introduction

Bioactivity
Description
Anti-Stabilin-2 Polyclonal Antibody is a Rabbit antibody targeting Stabilin-2. Anti-Stabilin-2 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
SynonymsSTAB-2, STAB 2, link domain-containing scavenger receptor 2, laminin-type EGF-like and link domain-containing scavenger receptor 2, Hyaluronan receptor for endocytosis, HARE, FEX2, FELL, FEEL-2, FEEL2, Fasciclin, FAS1 EGF-like and X-link domain-containing adhesion molecule 2, EGF-like, 190 kDa hyaluronan receptor for endocytosis, 190 kDa form stabilin-2
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Cow,Rabbit,Sheep)
Verified Activity
Tissue/cell: mouse spleen tissue;4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-Stabilin 2 Polyclonal Antibody, Unconjugated (TMAB-01778) 1:200, overnight at 4°C; The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C. DAPI (5 μg/ml,blue) was used to stain the cell nucleus.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane. Cytoplasm. Only a small amount appears to be present at the cell surface.
Tissue SpecificityHighly expressed in sinusoidal endothelial cells of liver, spleen and lymph nodes. Also expressed in non SEC-cells such as HMDMs (monocyte-derivedmacrophages), HAMs (T-cell leukemia virus type 1-associated myelopathy), and several macrophage cell line.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThis gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq, Jul 2008].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Stabilin 2
Antigen Species
Human
Gene Name
STAB2
Gene ID
Protein Name
Stabilin-2
Uniprot ID
Biology Area
Endothelial,Surface Molecules
Function
Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.
Chemical Properties
Molecular WeightTheoretical: 154/275 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-Stabilin-2 Polyclonal Antibody | purchase Anti-Stabilin-2 Polyclonal Antibody | Anti-Stabilin-2 Polyclonal Antibody cost | order Anti-Stabilin-2 Polyclonal Antibody | Anti-Stabilin-2 Polyclonal Antibody molecular weight