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MPT0B390

Name: MPT0B390
Brand: TargetMol
SKU: T9963
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T9963Cas No. 1817802-18-8

MPT0B390 is an inhibitor of HDAC and a TIMP3 inducer inhibiting tumor growth, metastasis, and angiogenesis.

MPT0B390

🥰Excellent

Purity: 99.4%

Catalog No. T9963Cas No. 1817802-18-8

MPT0B390 is an inhibitor of HDAC and a TIMP3 inducer inhibiting tumor growth, metastasis, and angiogenesis.

Pack Size	Price	Availability
1 mg	$35	In Stock
5 mg	$89	In Stock
10 mg	$133	In Stock
25 mg	$226	In Stock
50 mg	$322	In Stock
1 mL x 10 mM (in DMSO)	$98	In Stock

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Batch Information

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Purity:99.4%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	MPT0B390 is an inhibitor of HDAC and a TIMP3 inducer inhibiting tumor growth, metastasis, and angiogenesis.
In vitro	MPT0B390 exhibits antiproliferative activity against human colon cancer cell line HCT116 (GI50 = 0.03 μM)[1].

Chemical Properties

Molecular Weight	375.4
Formula	C₁₇H₁₇N₃O₅S
Cas No.	1817802-18-8
Smiles	COc1ccc(cc1)S(=O)(=O)N1CCc2cc(\C=C\C(=O)NO)cnc12
Relative Density.	1.452 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 245 mg/mL (652.64 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6638 mL	13.3191 mL	26.6383 mL	133.1913 mL
5 mM	0.5328 mL	2.6638 mL	5.3277 mL	26.6383 mL
10 mM	0.2664 mL	1.3319 mL	2.6638 mL	13.3191 mL
20 mM	0.1332 mL	0.6660 mL	1.3319 mL	6.6596 mL
50 mM	0.0533 mL	0.2664 mL	0.5328 mL	2.6638 mL
100 mM	0.0266 mL	0.1332 mL	0.2664 mL	1.3319 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc