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Anti-Carboxypeptidase E Antibody (6X802)

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Catalog No. TMAY-00212
Alias carboxypeptidase E

Anti-Carboxypeptidase E Antibody (6X802) is a Rabbit antibody targeting Carboxypeptidase E. Anti-Carboxypeptidase E Antibody (6X802) can be used in ELISA.

Anti-Carboxypeptidase E Antibody (6X802)

Anti-Carboxypeptidase E Antibody (6X802)

😃Good
Catalog No. TMAY-00212Alias carboxypeptidase E
Anti-Carboxypeptidase E Antibody (6X802) is a Rabbit antibody targeting Carboxypeptidase E. Anti-Carboxypeptidase E Antibody (6X802) can be used in ELISA.
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100 μL$270 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Carboxypeptidase E Antibody (6X802) is a Rabbit antibody targeting Carboxypeptidase E. Anti-Carboxypeptidase E Antibody (6X802) can be used in ELISA.
Aliascarboxypeptidase E
Ig Type
Monoclonal Rabbit IgG
Clone
6X802
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human CPE (rhCPE; TMPY-01141; NP_001864.1; Met 1-Ser 453).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCarboxypeptidase E (CPE), also known as Carboxypeptidase H, is a peripheral membrane protein and a zinc metallocarboxypeptidase, and the conversion of proCPE into CPE occurs primarily in secretory vesicles. The active form of CPE cleaves C-terminal amino acid residues of the peptide, and is thus involved in the biosynthesis of peptide hormones and neurotransmitters including insulin, enkephalin, etc. The enzymatic activity is enhanced by millimolar concentrations of Co2+. It has also been proposed that membrane-associated carboxypeptidase E acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway.Its interaction with glycosphingolipid-cholesterol rafts at the TGN facilitates the targeting. Mutations in this gene are implicated in type II diabetes due to impaired glucose clearance and insulin resistance.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human CPE protein (TMPY-01141)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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