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Iopamidol

Name: Iopamidol
Brand: TargetMol
SKU: T1576
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T1576Cas No. 60166-93-0

Alias SQ-13396, Niopam, Isovue, Iopamiron, Iopamiro, B-15000

Iopamidol (SQ-13396) is a benzenedicarboxamide compound. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic.

Iopamidol

🥰Excellent

Purity: 99.8%

Catalog No. T1576Alias SQ-13396, Niopam, Isovue, Iopamiron, Iopamiro, B-15000Cas No. 60166-93-0

Iopamidol (SQ-13396) is a benzenedicarboxamide compound. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic.

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$31	In Stock	In Stock
100 mg	$48	In Stock	In Stock
500 mg	$129	In Stock	In Stock
1 g	$193	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.8%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Iopamidol (SQ-13396) is a benzenedicarboxamide compound. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic.
In vitro	Iopamidol significantly decreases the rate of atrial contraction to a greater extent than either formulation of iodixanol. Iopamidol decreases papillary muscle force development more than the sodium formulation of iodixanol[3].
In vivo	Iopamidol increases systolic blood pressure (SBP), mean arterial pressure (MAP), and peak left ventricular pressure (LVP). Iopamidol increases LVP and LV end diastolic pressure to a greater extent than the cationic formulation of iodixanol. Thus iopamidol affects cardiovascular parameters more than iodixanol[3].
Cell Research	Chondrocytes are plated on 96 well plates at a density of 1 x 106 cells/cm2 . After overnight incubation in standard tissue culture conditions, contrast agents (including iopamidol) are introduced to wells in varying concentrations. Following 16 hour incubation with PBS and contrast agents, chondrocyte viability is assessed using the Live/Dead stain kit and quantified using the CellTiter-Glo Luminescent Cell Viability Assay. (Only for Reference)
Synonyms	SQ-13396, Niopam, Isovue, Iopamiron, Iopamiro, B-15000

Chemical Properties

Molecular Weight	777.09
Formula	C₁₇H₂₂I₃N₃O₈
Cas No.	60166-93-0
Smiles	C(NC(CO)CO)(=O)C1=C(I)C(C(NC(CO)CO)=O)=C(I)C(NC([C@H](C)O)=O)=C1I
Relative Density.	2.281 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

H2O: 92 mg/mL (118.39 mM), Sonication is recommended.

DMSO: 93 mg/mL (119.68 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (4.25 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2869 mL	6.4343 mL	12.8685 mL	64.3426 mL
5 mM	0.2574 mL	1.2869 mL	2.5737 mL	12.8685 mL
10 mM	0.1287 mL	0.6434 mL	1.2869 mL	6.4343 mL
20 mM	0.0643 mL	0.3217 mL	0.6434 mL	3.2171 mL
50 mM	0.0257 mL	0.1287 mL	0.2574 mL	1.2869 mL
100 mM	0.0129 mL	0.0643 mL	0.1287 mL	0.6434 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc