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Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody
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Catalog No. TMAB-01960
Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody is a Rabbit antibody targeting Vesicular Acetylcholine Transporter. Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody can be used in WB.
Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody
Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody
😃Good
Catalog No. TMAB-01960
Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody is a Rabbit antibody targeting Vesicular Acetylcholine Transporter. Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody is a Rabbit antibody targeting Vesicular Acetylcholine Transporter. Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Rabbit) |
| Verified Activity | Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Rat Cerebrum tissue lysates Lane 3: Human SH-SY5Y cell lysates Primary: Anti-Vesicular Acetylcholine Transporter (TMAB-01960) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 57 kDa Observed band size: 60 kDa |
| Application | WB |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Multi-pass membrane protein. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Vesicular Acetylcholine Transporter (VAChT), (~70kD protein), belongs to the family of vesicular monoamine transporters(VMATs), which include VMAT1 and VMAT2 and the C.elegans putative ACh transporter unc-17. Members of this family function to concentrate neurotransmitters into synaptic vesicles through exchange of protons for neurotransmitters. VAChT is a functional transporter for the neurotransmitter acetylcholine(ACh). ACh is synthesized in the cytoplasm by choline acetyl transferase (ChAT) and transported by VAChT into synaptic vesicles where it is stored until released. After release from presynaptic nerve terminals ACh is hydrolyzed by extracellular ACh-esterases(AChE) to choline and acetate. VAChT mRNA is expressed in all known major cholinergic neurons in the central and peripheral nervous system. VAChT is abundantly expressed in the CNS and is mainly localized in small synaptic vesicles in cholinergic nerve terminals. VAChT provides a specific marker for cholinergic neurons for the study of cholinergic transmission in experimental models, in Alzheimer’s disease and other nervous system disorders. |
| Immunogen | KLH conjugated synthetic peptide: human VAT |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Molecular Neuropharmacology,Acetylcholine |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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