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TargetMol | Compound Library

Anti-Cancer Clinical Compound Library

Catalog No. L2120

During the past decades, we have witnessed many landmark discoveries and successes in cancer research and therapy,however, cancer is still a major health problem for human beings, and it often physically and emotionally brings pains and difficulties to those living with it. Cancer cells remain undifferentiated (continue to divide, causing more damage, and invading new tissue), lack normal cell signaling responses (loss of contact inhibition and evasion of programmed cell death), contain abnormal changes (genetic abnormalities) in chromatin, have altered energy metabolism, and induce vascularization (ensure a steady supply of oxygen and nutrients).

We carefully select 1735 anti-cancer compounds currently in clinical trial phases based on published literatures and database to form this collection that can be used for high throughput screening and high content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2120

Anti-Cancer Clinical Compound Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product Description Product Description

  • A unique collection of 1735 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity confirmed by pre-clinical research and all of them are currently in clinical trial phases, representing the cutting-edge treatments for cancers;
  • Effective tool for cancer research and drug repurposing screening;
  • Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc., in lung cancer, breast cancer, leukemia, lymphoma, etc.
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
Endogenous Metabolite
PI3K
DNA/RNA Synthesis
5-HT Receptor
VEGFR
CDK
EGFR
Akt
FLT
NF-κB
p38 MAPK
mTOR
ROS
JAK
Reactive Oxygen Species
FGFR
Epigenetic Reader Domain
Parasite
c-Met/HGFR
Topoisomerase
HDAC
Ras
PPAR
Antibacterial
Potassium Channel
Dopamine Receptor
ERK
Cytochromes P450
Caspase
BTK
PDGFR
COX
GPCR
Src
Sodium Channel
Aurora Kinase
Prostaglandin Receptor
Microtubule Associated
Histamine Receptor
Adenosine Receptor
PARP
Calcium Channel
Estrogen Receptor/ERR
Interleukin
Adrenergic Receptor
Tyrosine Kinases
Androgen Receptor
MDM-2/p53
Raf
Wnt/beta-catenin
iGluR
TGF-beta/Smad
HSP
Bcl-2 Family
GABA Receptor
P-gp
TNF
STAT
c-Kit
Histone Methyltransferase
Virus Protease
HIV Protease
Dehydrogenase
Bcr-Abl
PKC
Drug Metabolite
E1/E2/E3 Enzyme
ATM/ATR
p53
Phosphatase
Mitochondrial Metabolism
Nucleoside Antimetabolite/Analog
CXCR
MMP
MAPK
AMPK
MEK
ALK
FAK
Estrogen/progestogen Receptor
GSK-3
Antioxidant
Chk
IGF-1R
Influenza Virus
c-Fms
HIF/HIF Prolyl-Hydroxylase
PROTACs
JNK
TRP/TRPV Channel
TLR
Molecular Glues
AChR
TAM Receptor
HER
KRas
SARS-CoV
AXL
Beta Amyloid
Antibiotic
DNA-PK
Ferroptosis
IAP
NMDAR
Gamma-secretase
Opioid Receptor
HSV
Trk receptor
c-RET
Cannabinoid Receptor
S6 Kinase
Kinesin
HCV Protease
ATPase
Antifungal
Histone Demethylase
PERK
PKA
ROCK
IDO
Glucocorticoid Receptor
IL Receptor
Indoleamine 2,3-Dioxygenase (IDO)
Antiviral
NOD
ROS Kinase
Mdm2
Transferase
RIP kinase
PDE
GluR
Endothelin Receptor
OX Receptor
Casein Kinase
PLK
HIF
Syk
NOD-like Receptor (NLR)
LPL Receptor
PYK2
Pim
CSF-1R
Sirtuin
IRAK
Integrin
Mitophagy
P2X Receptor
Guanylate cyclase
Vasopressin Receptor
Lipoxygenase
CCR
NO Synthase
Nrf2
PD-1/PD-L1
S1P Receptor
Carbonic Anhydrase
Serine Protease
Antifolate
Cholecystokinin Receptor
Glucagon Receptor
Bradykinin Receptor
OXPHOS
Ligands for E3 Ligase
Hedgehog/Smoothened
PAK
CFTR
Sigma receptor
Monoamine Oxidase
Reductase
Tie-2
ADC Cytotoxin
IFNAR
Photosensitizer
HBV
Leukotriene Receptor
NAMPT
Glutaminase
Smo
IKZF
Neuropeptide Y Receptor
DNA Alkylation
STING
Isocitrate Dehydrogenase (IDH)
SGLT
Wee1
Survivin
Ephrin Receptor
PDK
MLK
CRFR
Reverse Transcriptase
Retinoid Receptor
Discoidin Domain Receptor (DDR)
Anti-infection
Tyrosinase
DHFR
P2Y Receptor
DYRK
Proton pump
NEDD8
MAO
Serotonin Transporter
Liver X Receptor
FXR
Aryl Hydrocarbon Receptor
KSP
DUB
Acyltransferase
Telomerase
MNK
Porcupine
RSV
Melanocortin Receptor
GHSR
DNA Methyltransferase
Chloride channel
Monocarboxylate transporter
CRM1
DNA Alkylator/Crosslinker
Progesterone Receptor
c-Myc
Kisspeptin
Proteasome
YAP
LTR
MIF
Galectin
CaSR
Serine/threonin kinase
Glucokinase
UGT
Bcl-6
Neurotensin Receptor
LIM Kinase
Immunology/Inflammation related
SIK
Glucosidase
glycosidase
DNA
BCRP
PSMA
GPCR19
transporter
Cholinesterase (ChE)
Cadherin
Norepinephrine
Histone Acetyltransferase
IκB/IKK
LPA Receptor
PI4K
CGRP Receptor
SGK
p97
AhR
Aromatase
Hydroxylase
NOS
ADAM
MALT
ROR
NADPH
RAAS
Glutathione Peroxidase
TOPK
GTPase
Apelin receptor
Advanced Glycation End Products
MyD88
Factor VIIa
Necroptosis
VDA
Factor Xa
GNRH Receptor
Stemness kinase
Prolyl Endopeptidase (PREP)
Myosin
IRE1
Anion Exchanger
N-Acetylglucosaminyltransferase
MRP
Rho
Cell Cycle Arrest
Adenylate cyclase
ABC Transporter
Na-K-Cl cotransporter
GlyT
Antifection
Hexokinase
HCN Channel
DPP-4
Fatty Acid Synthase
ACK1
Angiotensin-converting Enzyme (ACE)
Somatostatin
Xanthine Oxidase
ATP Citrate Lyase
Beta-Secretase
PGE Synthase
PROTAC Linker
Thioredoxin
PTEN
Lipid
Huntingtin
OAT
E3 Ligase Ligand-Linker Conjugates
Aminopeptidase
CD73
Pyroptosis
Methionine Adenosyltransferase (MAT)
GST
KLF
Dipeptidyl Peptidase
Cuproptosis
HMG-CoA Reductase
Protease-activated Receptor
ASK
PAI-1
MELK
Hippo pathway
GPX
CRISPR/Cas9
Phospholipase
Oxytocin Receptor
Aquaporin
FOXO
RXFP receptor
GSPT1
Neurokinin receptor
Gap Junction Protein
BMI-1
Liposome
Imidazoline Receptor
Vitamin

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