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TargetMol | Compound Library

Anti-Cancer Clinical Compound Library

Catalog No. L2120

During the past decades, we have witnessed many landmark discoveries and successes in cancer research and therapy,however, cancer is still a major health problem for human beings, and it often physically and emotionally brings pains and difficulties to those living with it. Cancer cells remain undifferentiated (continue to divide, causing more damage, and invading new tissue), lack normal cell signaling responses (loss of contact inhibition and evasion of programmed cell death), contain abnormal changes (genetic abnormalities) in chromatin, have altered energy metabolism, and induce vascularization (ensure a steady supply of oxygen and nutrients).

We carefully select 2760 anti-cancer compounds currently in clinical trial phases based on published literatures and database to form this collection that can be used for high throughput screening and high content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2120

Anti-Cancer Clinical Compound Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product Description Product Description

  • A unique collection of 2760 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity confirmed by pre-clinical research and all of them are currently in clinical trial phases, representing the cutting-edge treatments for cancers;
  • Effective tool for cancer research and drug repurposing screening;
  • Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc., in lung cancer, breast cancer, leukemia, lymphoma, etc.
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

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Apoptosis
Autophagy
Endogenous Metabolite
5-HT Receptor
Antibacterial
Adrenergic Receptor
DNA/RNA Synthesis
Dopamine Receptor
Antibiotic
VEGFR
COX
Potassium Channel
Histamine Receptor
Calcium Channel
EGFR
Parasite
Sodium Channel
PI3K
ROS
CDK
Cytochromes P450
Reactive Oxygen Species
NF-κB
FLT
JAK
PDGFR
HIV Protease
Glucocorticoid Receptor
FGFR
Topoisomerase
c-Kit
mTOR
HDAC
Akt
Microtubule Associated
c-Met/HGFR
PPAR
Ferroptosis
Virus Protease
AChR
Prostaglandin Receptor
SARS-CoV
Src
p38 MAPK
Dehydrogenase
GABA Receptor
Nucleoside Antimetabolite/Analog
Estrogen Receptor/ERR
Mitophagy
ERK
Antifungal
Interleukin
iGluR
Estrogen/progestogen Receptor
Bcr-Abl
Adenosine Receptor
Tyrosine Kinases
Influenza Virus
Caspase
Androgen Receptor
Ras
Epigenetic Reader Domain
Raf
GPCR
TNF
PARP
BTK
P-gp
HSP
HSV
Aurora Kinase
PDE
Serotonin Transporter
Bcl-2 Family
ALK
MDM-2/p53
TRP/TRPV Channel
MEK
HER
HBV
Trk receptor
HIF/HIF Prolyl-Hydroxylase
Opioid Receptor
RAAS
c-RET
Histone Methyltransferase
PKC
STAT
Mitochondrial Metabolism
Phosphatase
Norepinephrine
TLR
ATPase
Wnt/beta-catenin
c-Fms
HCV Protease
Endothelin Receptor
AMPK
ROS Kinase
NMDAR
JNK
E1/E2/E3 Enzyme
DNA Alkylator/Crosslinker
GSK-3
TAM Receptor
Drug Metabolite
FAK
Beta Amyloid
MMP
Chk
Proton pump
Retinoid Receptor
LPL Receptor
Molecular Glues
Progesterone Receptor
Gamma-secretase
S1P Receptor
Kras
Guanylate cyclase
CXCR
NO Synthase
TGF-beta/Smad
SGLT
Reverse Transcriptase
HIF
GluR
IGF-1R
CFTR
Nrf2
p53
DNA-PK
Antifolate
Carbonic Anhydrase
IL Receptor
Proteasome
PKA
DNA Alkylation
ATM/ATR
P2X Receptor
ROCK
S6 Kinase
Antioxidant
Syk
Hedgehog/Smoothened
HMG-CoA Reductase
ADC Cytotoxin
GNRH Receptor
Vasopressin Receptor
IAP
PLK
DHFR
Integrin
CSF-1R
Ligands for E3 Ligase
Indoleamine 2,3-Dioxygenase (IDO)
Kinesin
Transferase
IDO
Anti-infection
Monoamine Oxidase
Mdm2
MAO
Isocitrate Dehydrogenase (IDH)
Lipoxygenase
P2Y Receptor
Angiotensin-converting Enzyme (ACE)
MAPK
Glutathione Peroxidase
Leukotriene Receptor
Cannabinoid Receptor
IκB/IKK
MRP
Antifection
OX Receptor
DNA Methyltransferase
PAK
IRAK
Histone Demethylase
Sirtuin
Casein Kinase
Serine Protease
Smo
Phospholipase
RIP kinase
Antiviral
DNA
Hydroxylase
Sigma receptor
FXR
Bradykinin Receptor
Reductase
Tie-2
Neurokinin receptor
Pim
Ephrin Receptor
PD-1/PD-L1
PROTACs
CCR
Glucagon Receptor
IKZF
Serine/threonin kinase
Xanthine Oxidase
STING
Tyrosinase
PYK2
Wee1
IFNAR
Telomerase
Thrombin
NOD-like Receptor (NLR)
CRFR
GHSR
NOD
PERK
Cholinesterase (ChE)
DPP-4
GPCR19
RSV
Chloride channel
Melatonin Receptor
Aryl Hydrocarbon Receptor
CGRP Receptor
Cholecystokinin Receptor
Glucosidase
CRM1
Glutaminase
Fatty Acid Synthase
Somatostatin
PGE Synthase
YAP
NADPH
Na-K-Cl cotransporter
Neuropeptide Y Receptor
CaMK
AhR
Photosensitizer
NAMPT
GST
Aromatase
Oxytocin Receptor
ABC Transporter
Monoamine Transporter
glycosidase
DUB
IRE1
KSP
OXPHOS
Free radical scavengers
FKBP
MLK
Beta-Secretase
Decarboxylase
Adenosine Deaminase
BCRP
Survivin
Aminopeptidase
Cuproptosis
Discoidin Domain Receptor (DDR)
Protease-activated Receptor
Annexin A
MT Receptor
transporter
c-Myc
CaSR
Rho
Melanocortin Receptor
Gap Junction Protein
LTR
ATP Citrate Lyase
ribosome
ROR
OAT
NOS
Monocarboxylate transporter
Cysteine Protease
LDL
DNA gyrase
Huntingtin
TOPK
Acyltransferase
UGT
Thrombopoietin Receptor
p97
Necroptosis
RANKL/RANK
GRK
LPA Receptor
PDK
SGK
Arginase
DYRK
HCN Channel
Histone Acetyltransferase
PAI-1
NEDD8
VDA
PROTAC Linker
Porcupine
CD73
Amino Acids and Derivatives
Ligands for Target Protein for PROTAC
Galectin
Hexokinase
PI4K
Complement System
PGC-1α
RAR/RXR
MALT
MyD88
Cadherin
GluCls
Pyroptosis
RXFP receptor
NADPH-oxidase
Thyroid hormone receptor(THR)
NPC1L1
Kisspeptin
Myosin
Thioredoxin
Neprilysin
FOXO
Liposome
MIF
Neurotensin Receptor
Adenylate cyclase
GlyT
ASK
Methionine Adenosyltransferase (MAT)
Aquaporin
Advanced Glycation End Products
Cell wall
OCT
Hck
Stemness kinase
ACK1
Lipid
PSMA
BMI-1
GTPase
Factor Xa
Liver X Receptor
MELK
Hydrogenase
Factor VIIa
N-Acetylglucosaminyltransferase
ATG
Anion Exchanger
E3 Ligase Ligand-Linker Conjugates
Hippo pathway
Imidazoline Receptor
MicroRNA
Cell Cycle Arrest
LIM Kinase
Glucokinase
PAFR
MTH1
HCAR
MNK
KLF
Ferroportin
Vitamin
Drug-Linker Conjugates for ADC

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