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Anti-Prostatic Acid Phosphatase Antibody (6C236)

😃Good
Catalog No. TMAY-03523
Alias Ppal, PAP, Lap, FRAP, acid phosphatase, prostate, A030005E02Rik, 9.104100899-104272570.1, 5'-NT

Anti-Prostatic Acid Phosphatase Antibody (6C236) is a Rabbit antibody targeting Prostatic Acid Phosphatase. Anti-Prostatic Acid Phosphatase Antibody (6C236) can be used in ELISA(Cap).

Anti-Prostatic Acid Phosphatase Antibody (6C236)

Anti-Prostatic Acid Phosphatase Antibody (6C236)

😃Good
Catalog No. TMAY-03523Alias Ppal, PAP, Lap, FRAP, acid phosphatase, prostate, A030005E02Rik, 9.104100899-104272570.1, 5'-NT
Anti-Prostatic Acid Phosphatase Antibody (6C236) is a Rabbit antibody targeting Prostatic Acid Phosphatase. Anti-Prostatic Acid Phosphatase Antibody (6C236) can be used in ELISA(Cap).
Pack SizePriceAvailabilityQuantity
20 μL$93 7-10 days
100 μL$268 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Prostatic Acid Phosphatase Antibody (6C236) is a Rabbit antibody targeting Prostatic Acid Phosphatase. Anti-Prostatic Acid Phosphatase Antibody (6C236) can be used in ELISA(Cap).
AliasPpal, PAP, Lap, FRAP, acid phosphatase, prostate, A030005E02Rik, 9.104100899-104272570.1, 5'-NT
Ig Type
Monoclonal Rabbit IgG
Clone
6C236
Reactivity
Mouse
Application
ELISA(Cap)
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse Prostatic Acid Phosphatase/ACPP (rM Prostatic Acid Phosphatase/ACPP; TMPY-02672; Q8CE08-1; Met1-Arg381).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundProstatic acid phosphatase (PAP, or ACPP), also known as prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. As a non-specific phosphomonoesterase, Prostatic acid phosphatase is synthesized and secreted into seminal plasma under androgenic control. The enzyme is a dimer of molecular weight around 100 kDa. Prostatic acid phosphatase is a clinically important protein for its relevance as a biomarker of prostate carcinoma. Furthermore, it has a potential role in fertilization. The major action of PAP is to dephosphorylate macromolecules with the help of catalytic residues (His(12) and Asp(258)) that are located in the cleft between two domains. Cellular prostatic acid phosphatase (cPAcP), an authentic tyrosine phosphatase, is proposed to function as a negative growth regulator of prostate cancer (PCa) cells in part through its dephosphorylation of ErbB-2. cPAcP functions as a neutral protein tyrosine phosphatase (PTP) in prostate cancer cells and dephosphorylates HER-2/ErbB-2/Neu (HER-2: human epidermal growth factor receptor-2) at the phosphotyrosine (p-Tyr) residues. Injection of the secretory isoform of PAP has potent antinociceptive effects in mouse models of chronic pain. This enzyme exhibits ecto-5'-nucleotidase activity, is widely distributed, and implicated in the formation of chronic pain. Additionally, PAP could be a target molecule in specific immunotherapy for patients with nonprostate adenocarcinomas including colon and gastric cancers.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse Prostatic Acid Phosphatase/ACPP Protein (TMPY-02672)
Antigen Species
Mouse
Biology Area
Phosphatases and Regulators
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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