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Anti-SLC5A5 Polyclonal Antibody is a Rabbit antibody targeting SLC5A5. Anti-SLC5A5 Polyclonal Antibody can be used in IF,IHC-Fr,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
| Description | Anti-SLC5A5 Polyclonal Antibody is a Rabbit antibody targeting SLC5A5. Anti-SLC5A5 Polyclonal Antibody can be used in IF,IHC-Fr,WB. |
| Synonyms | Solute carrier family 5 member 5, Sodium-iodide symporter (Na(+)/I(-) symporter), Sodium/iodide cotransporter, SLC5A5, NIS, Natrium iodide transporter, Na(+)/I(-) cotransporter |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human) |
| Verified Activity | Sample: Lane 1: Mouse Stomach tissue lysates Lane 2: Rat Stomach tissue lysates Primary: Anti-NIS (TMAB-01727) at 1/200 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 68 kDa Observed band size: 48 kDa ![]() |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | catalyzes Na+/I- symporter activity plays a role in iodide transport and thyroid hormone generation. Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid. |
| Immunogen | KLH conjugated synthetic peptide: human NIS |
| Antigen Species | Human |
| Gene Name | SLC5A5 |
| Gene ID | |
| Protein Name | Sodium/iodide cotransporter |
| Uniprot ID | |
| Biology Area | Vitamins / Minerals,Channels,Hormone biosynthesis,Vitamins / minerals,Hormone biosynthesis |
| Function | Mediates iodide uptake in the thyroid gland. |
| Molecular Weight | Theoretical: 68 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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