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Anti-SLC5A5 Polyclonal Antibody

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Catalog No. TMAB-01727
Alias Solute carrier family 5 member 5, Sodium-iodide symporter (Na(+)/I(-) symporter), Sodium/iodide cotransporter, SLC5A5, NIS, Natrium iodide transporter, Na(+)/I(-) cotransporter

Anti-SLC5A5 Polyclonal Antibody is a Rabbit antibody targeting SLC5A5. Anti-SLC5A5 Polyclonal Antibody can be used in IF,IHC-Fr,WB.

Anti-SLC5A5 Polyclonal Antibody

Anti-SLC5A5 Polyclonal Antibody

😃Good
Catalog No. TMAB-01727Alias Solute carrier family 5 member 5, Sodium-iodide symporter (Na(+)/I(-) symporter), Sodium/iodide cotransporter, SLC5A5, NIS, Natrium iodide transporter, Na(+)/I(-) cotransporter
Anti-SLC5A5 Polyclonal Antibody is a Rabbit antibody targeting SLC5A5. Anti-SLC5A5 Polyclonal Antibody can be used in IF,IHC-Fr,WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-SLC5A5 Polyclonal Antibody is a Rabbit antibody targeting SLC5A5. Anti-SLC5A5 Polyclonal Antibody can be used in IF,IHC-Fr,WB.
SynonymsSolute carrier family 5 member 5, Sodium-iodide symporter (Na(+)/I(-) symporter), Sodium/iodide cotransporter, SLC5A5, NIS, Natrium iodide transporter, Na(+)/I(-) cotransporter
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human)
Verified Activity
Sample:
Lane 1: Mouse Stomach tissue lysates
Lane 2: Rat Stomach tissue lysates
Primary: Anti-NIS (TMAB-01727) at 1/200 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 68 kDa
Observed band size: 48 kDa
verifiedActivity
Application
Recommended Dose
WB: 1:500-2000; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Multi-pass membrane protein.
Tissue SpecificityExpression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research Backgroundcatalyzes Na+/I- symporter activity plays a role in iodide transport and thyroid hormone generation. Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human NIS
Antigen Species
Human
Gene Name
SLC5A5
Gene ID
Protein Name
Sodium/iodide cotransporter
Uniprot ID
Biology Area
Vitamins / Minerals,Channels,Hormone biosynthesis,Vitamins / minerals,Hormone biosynthesis
Function
Mediates iodide uptake in the thyroid gland.
Chemical Properties
Molecular WeightTheoretical: 68 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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