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Anti-RPA1 Antibody (1L894)

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Catalog No. TMAC-03629

Anti-RPA1 Antibody (1L894) is a Rabbit antibody targeting RPA1. Anti-RPA1 Antibody (1L894) can be used in WB,ICC,IF,FCM.

Anti-RPA1 Antibody (1L894)

Anti-RPA1 Antibody (1L894)

😃Good
Catalog No. TMAC-03629
Anti-RPA1 Antibody (1L894) is a Rabbit antibody targeting RPA1. Anti-RPA1 Antibody (1L894) can be used in WB,ICC,IF,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-RPA1 Antibody (1L894) is a Rabbit antibody targeting RPA1. Anti-RPA1 Antibody (1L894) can be used in WB,ICC,IF,FCM.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:500; ICC: 1:50-100; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe single-stranded-DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells, mitochondria, phages and viruses. Replication protein A (RPA), a highly conserved eukaryotic protein, is a heterotrimeric SSB. RPA plays an important role in DNA replication, recombination and repair. The binding of human RPA (hRPA) to DNA involves molecular polarity in which initial hRPA binding occurs on the 5' side of an ssDNA substrate and then extends in the 3' direction to create a stably bound hRPA. RPA is a major damage-recognition protein involved in the early stages of nucleotide excision repair. It can also play a role in telomere maintenance. The RPA 70 kDa subunit binds to ssDNA and mediates interactions with many cellular and viral proteins. The DNA binding domain lies in the middle of RPA 70 kDa subunit and comprises two structurally homologous subdomains oriented in tandem. RPA contains a conserved four cysteine-type zinc-finger motif, which mediates the transition of RPA-ssDNA interaction to a stable RPA-ssDNA complex in a redox-dependent manner.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 68 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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