Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KP-457 (TNF-α-converting enzyme) is a selective inhibitor of ADAM17, with an IC50 value of 11.1 nM/L in cell-free assays. The compound can also cleave a variety of molecules, including GPIbα, GPV and TNF-α.
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Description | KP-457 (TNF-α-converting enzyme) is a selective inhibitor of ADAM17, with an IC50 value of 11.1 nM/L in cell-free assays. The compound can also cleave a variety of molecules, including GPIbα, GPV and TNF-α. |
Synonyms | TNF‐α‐converting enzyme |
Molecular Weight | 480.56 |
Formula | C21H24N2O7S2 |
CAS No. | 1365803-52-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
KP-457 1365803-52-6 TNF‐α‐converting enzyme KP457 KP 457 inhibitor inhibit