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DBCO-PEG3-NHS ester

Name: DBCO-PEG3-NHS ester
Brand: TargetMol
SKU: T17791
Price: 107 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T17791Cas No. 2163772-16-3

DBCO-PEG3-NHS ester is a degradable ADC linker that can be used to synthesize antibody-coupled active molecules.

DBCO-PEG3-NHS ester

🥰Excellent

Purity: 97.41%

Catalog No. T17791Cas No. 2163772-16-3

DBCO-PEG3-NHS ester is a degradable ADC linker that can be used to synthesize antibody-coupled active molecules.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$107	-	In Stock
5 mg	$269	-	In Stock
10 mg	$395	-	In Stock
25 mg	$592	-	In Stock
50 mg	$833	-	In Stock
100 mg	$1,120	-	In Stock
200 mg	$1,520	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:97.41%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	DBCO-PEG3-NHS ester is a degradable ADC linker that can be used to synthesize antibody-coupled active molecules.
In vitro	Comprised of an antibody, an ADC cytotoxin is attached through an ADC linker[1].

Chemical Properties

Molecular Weight	605.64
Formula	C₃₂H₃₅N₃O₉
Cas No.	2163772-16-3
Smiles	O=C(ON1C(=O)CCC1=O)CCOCCOCCOCCNC(=O)CCC(=O)N2C=3C=CC=CC3C#CC=4C=CC=CC4C2
Relative Density.	1.35 g/cm3 (Predicted)
Color	Yellow
Appearance	Oil

Storage & Solubility Information

Storage

store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc