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Serpin B6 Protein, Human, Recombinant (E. coli, His)

Catalog No. TMPJ-00243
Synonyms: CAP, PI6, SERPINB6, Placental Thrombin Inhibitor, Cytoplasmic Antiproteinase, PI-6, Serpin B6, PTI, Peptidase Inhibitor 6

Serpin B6 belongs to the serpin family. Serpin B6 localizes to the cytoplasm. Serpin B6 is expressed in many tissues, abundantly by mast cells in different tissues and mastocytoma lesions. Serpin B6 may be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. In addition, Serpin B6 may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.

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Serpin B6 Protein, Human, Recombinant (E. coli, His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Serpin B6 belongs to the serpin family. Serpin B6 localizes to the cytoplasm. Serpin B6 is expressed in many tissues, abundantly by mast cells in different tissues and mastocytoma lesions. Serpin B6 may be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. In addition, Serpin B6 may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.
Species Human
Expression System E. coli
Tag N-Trx-6His
Accession Number AAH01394.1
Synonyms CAP, PI6, SERPINB6, Placental Thrombin Inhibitor, Cytoplasmic Antiproteinase, PI-6, Serpin B6, PTI, Peptidase Inhibitor 6
Amino Acid Met1-Pro376
Construction Recombinant Human Serine Protease Inhibitor-clade B6 is produced by our E.coli expression system and the target gene encoding Met1-Pro376 is expressed with a Trx, 6His tag at the N-terminus.
Protein Purity Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 58-60 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 50mM Tris-HCl, 10mM CaCl<sub>2</sub>, 150mM NaCl, 0.05% Brij-35, pH7.5.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Research Background Serpin B6 belongs to the serpin family. Serpin B6 localizes to the cytoplasm. Serpin B6 is expressed in many tissues, abundantly by mast cells in different tissues and mastocytoma lesions. Serpin B6 may be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. In addition, Serpin B6 may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.

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Keywords

Serpin B6 Protein, Human, Recombinant (E. coli, His) CAP PI6 SERPINB6 Placental Thrombin Inhibitor Cytoplasmic Antiproteinase PI-6 Serpin B6 SERPINB-6 PI 6 PTI SERPINB 6 Peptidase Inhibitor 6 recombinant recombinant-proteins proteins protein

 

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