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Anti-TLR4 Polyclonal Antibody 3 (Synonyms: toll-like receptor 4, TOLL, TLR-4, TLR4, CD284, ARMD10)
Catalog No. TMAB-01856 Copy Product Info
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Anti-TLR4 Polyclonal Antibody 3 is a Rabbit antibody targeting TLR4. Anti-TLR4 Polyclonal Antibody 3 can be used in IF, IHC-Fr, IHC-P, WB.
Anti-TLR4 Polyclonal Antibody 3
Copy Product Info🥰Excellent
Catalog No. TMAB-01856
Synonyms toll-like receptor 4, TOLL, TLR-4, TLR4, CD284, ARMD10
Anti-TLR4 Polyclonal Antibody 3 is a Rabbit antibody targeting TLR4. Anti-TLR4 Polyclonal Antibody 3 can be used in IF, IHC-Fr, IHC-P, WB.
Anti-TLR4 Polyclonal Antibody 3
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-TLR4 Polyclonal Antibody 3 is a Rabbit antibody targeting TLR4. Anti-TLR4 Polyclonal Antibody 3 can be used in IF, IHC-Fr, IHC-P, WB. |
| Synonyms | toll-like receptor 4, TOLL, TLR-4, TLR4, CD284, ARMD10 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Pig,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | 1. This image was generously provided by Juanli Fu, at Southwest University in Chong Qing, China. 4% Paraformaldehyde fixed PC12 cells stained with Rabbit Anti-TLR4 Polyclonal Antibody (TMAB-01856) at 1:300 for 3 hours at 4°C, followed by Alexa Fluor 488-conjugated secondary antibody for an additional hour. 2. Sample: K562 (Human) Cell Lysate at 40 μg HL-60 (Human) Cell Lysate at 40 μg RAW264.7 (Mouse) Cell Lysate at 40 μg Primary: Anti-TLR4 (TMAB-01856) at 1/2000 dilution   |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC-P: 1:100-500; IHC-Fr: 1:500-1000; IF: 1:200-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Highly expressed in placenta, spleen and peripheral blood leukocytes. Detected in monocytes, macrophages, dendritic cells and several types of T-cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The Toll-like receptor 4 by activating natural immunity, specific immune response involved in the start-up, Toll-like receptor 4 as an important signal transduction transmembrane receptor involved in the toxin-induced inflammation in the pathological process, its mechanisms of control On a growing concern. all regions were either double-stranded or sequenced with an alternatechemistry or covered by high quality data(i.e., phred quality >=30); an attempt was made to resolve all sequencing problems, such as compressions and repeats; all regions were covered by at least one subclone; and the assembly was confirmed by restriction digest, except on the rare occasion of the clone being a YAC. The following abbreviations are used to associate primary accession numbers given in the feature table with their source databases: Em:, EMBL; Sw:, SWISSPROT; Tr:, TREMBL; Wp:, WORMPEP; Information on the WORMPEP database can be found at. TLR-4 plays an important role in microvascular leakage and leukocyte adhesion under the inflammatory condition associated with nonseptic thermal injury. |
| Immunogen | KLH conjugated synthetic peptide: human TLR4 |
| Antigen Species | Human |
| Gene Name | TLR4 |
| Gene ID | |
| Protein Name | Toll-like receptor 4 |
| Uniprot ID | |
| Biology Area | Inflammatory mediators,Regulatory T Cells,Receptors,Macrophage / Inflamm.,TLR Signaling,Host Virus Interaction |
| Function | Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by Ni(2+). These responses require non-conserved histidines and are, therefore, species-specific. |
| Molecular Weight | Theoretical: 90 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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