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Anti-CCL19/MIP-3b Antibody (4C246) (Synonyms: Scya19, MIP3B, exodus-3, ELC, CKb11, chemokine (C-C motif) li...)
Catalog No. TMAH-00149 Copy Product Info
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Anti-CCL19/MIP-3b Antibody (4C246) is an antibody targeting CCL19/MIP-3b. Anti-CCL19/MIP-3b Antibody (4C246) can be used in ELISA,IHC.
Anti-CCL19/MIP-3b Antibody (4C246)
Copy Product Info🥰Excellent
Catalog No. TMAH-00149
Synonyms Scya19, MIP3B, exodus-3, ELC, CKb11, chemokine (C-C motif) ligand 19
Anti-CCL19/MIP-3b Antibody (4C246) is an antibody targeting CCL19/MIP-3b. Anti-CCL19/MIP-3b Antibody (4C246) can be used in ELISA,IHC.
Anti-CCL19/MIP-3b Antibody
(4C246)
(4C246)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-CCL19/MIP-3b Antibody (4C246) is an antibody targeting CCL19/MIP-3b. Anti-CCL19/MIP-3b Antibody (4C246) can be used in ELISA,IHC. |
| Synonyms | Scya19, MIP3B, exodus-3, ELC, CKb11, chemokine (C-C motif) ligand 19 |
| Ig Type | Rabbit IgG |
| Clone | 4C246 |
| Reactivity | Human |
| Verified Activity | 1. IHC image of TMAH-00149 diluted at 1:155 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. 2. IHC image of TMAH-00149 diluted at 1:155 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Application | |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human CCL19 |
| Antigen Species | Human |
| Gene Name | CCL19 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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