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Anti-CCL19/MIP-3b Antibody (4C246) is an antibody targeting CCL19/MIP-3b. Anti-CCL19/MIP-3b Antibody (4C246) can be used in ELISA, IHC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $208 | 7-10 days | |
100 μL | $349 | 7-10 days |
Description | Anti-CCL19/MIP-3b Antibody (4C246) is an antibody targeting CCL19/MIP-3b. Anti-CCL19/MIP-3b Antibody (4C246) can be used in ELISA, IHC. |
Alias | Scya19, MIP3B, exodus-3, ELC, CKb11, chemokine (C-C motif) ligand 19 |
Ig Type | Rabbit IgG |
Clone | 4C246 |
Reactivity | Human |
Verified Activity | 1. IHC image of TMAH-00149 diluted at 1:155 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. 2. IHC image of TMAH-00149 diluted at 1:155 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Application | ELISA, IHC |
Recommended Dose | IHC:1:50-1:200. |
Antibody Type | Monoclonal |
Subcellular Localization | Secreted. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide: Human CCL19 |
Antigen Species | Human |
Gene ID | 6363 |
Uniprot ID | |
Biology Area | Immunology |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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