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Anti-ADIPOR1 Polyclonal Antibody (Synonyms: TESBP1A, Progestin and adipoQ receptor family member I, Progestin ...)
Catalog No. TMAB-00064 Copy Product Info
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Anti-ADIPOR1 Polyclonal Antibody is a Rabbit antibody targeting ADIPOR1. Anti-ADIPOR1 Polyclonal Antibody can be used in IF,IHC-Fr,WB.
Anti-ADIPOR1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-00064
Synonyms TESBP1A, Progestin and adipoQ receptor family member I, Progestin and adipoQ receptor family member 1, PAQR1, ADIPOR1, Adiponectin receptor protein 1
Anti-ADIPOR1 Polyclonal Antibody is a Rabbit antibody targeting ADIPOR1. Anti-ADIPOR1 Polyclonal Antibody can be used in IF,IHC-Fr,WB.
Anti-ADIPOR1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ADIPOR1 Polyclonal Antibody is a Rabbit antibody targeting ADIPOR1. Anti-ADIPOR1 Polyclonal Antibody can be used in IF,IHC-Fr,WB. |
| Synonyms | TESBP1A, Progestin and adipoQ receptor family member I, Progestin and adipoQ receptor family member 1, PAQR1, ADIPOR1, Adiponectin receptor protein 1 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Dog,Rabbit) |
| Verified Activity | 1. Sample: Muscle (Mouse) Lysate at 40 μg Primary: Anti-Adiponectin Receptor 1 (TMAB-00064) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kDa Observed band size: 42 kDa 2. Sample: Lane 1: Mouse Muscle tissue lysates Lane 2: Mouse Breast tissue lysates Lane 3: Mouse Heart tissue lysates Lane 4: Rat Muscle tissue lysates Lane 5: Rat Heart tissue lysates Primary: Anti-Adiponectin Receptor 1 (TMAB-00064) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kDa Observed band size: 42 kDa   |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Multi-pass membrane protein. Note=Localized to the cell membrane and intracellular organelles. |
| Tissue Specificity | Widely expressed. Highly expressed in skeletal muscle. Expressed at intermediate level in brain, heart, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. Weakly expressed in colon, thymus and small intestine. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Acrp30 is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Levels of adiponectin in the blood are decreased under conditions of obesity, insulin resistance and type 2 diabetes. Administration of adiponectin causes glucose-lowering effects and ameliorates insulin resistance in mice. Conversely, adiponectin-deficient mice exhibit insulin resistance and diabetes. This insulin-sensitizing effect of adiponectin seems to be mediated by an increase in fatty-acid oxidation through activation of AMP kinase and PPAR- . Cloning of complementary DNAs encoding adiponectin receptors 1 and 2 (AdipoR1 and AdipoR2) have shown that AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. |
| Immunogen | KLH conjugated synthetic peptide: human Adiponectin Receptor 1 |
| Antigen Species | Human |
| Gene Name | ADIPOR1 |
| Gene ID | |
| Protein Name | Adiponectin receptor protein 1 |
| Uniprot ID | |
| Biology Area | Acrp,Hormones |
| Function | Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin. |
| Molecular Weight | Theoretical: 42 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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