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DBCO-PEG12-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $44 | In Stock | |
5 mg | $105 | In Stock | |
10 mg | $153 | In Stock | |
25 mg | $259 | In Stock | |
50 mg | $417 | In Stock | |
100 mg | $669 | In Stock | |
200 mg | $933 | In Stock |
Description | DBCO-PEG12-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, which consist of two ligands connected by a linker—one targeting an E3 ubiquitin ligase and the other the target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Cas No. | 2093934-94-0 |
Relative Density. | no data available |
Color | Brown |
Appearance | Viscous |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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