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Anti-Phospho-VE-Cadherin (Tyr731) Polyclonal Antibody is a Rabbit antibody targeting Phospho-VE-Cadherin (Tyr731). Anti-Phospho-VE-Cadherin (Tyr731) Polyclonal Antibody can be used in IF,IHC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $217 | 7-10 days | 7-10 days | |
| 100 μL | $317 | 7-10 days | 7-10 days |
| Description | Anti-Phospho-VE-Cadherin (Tyr731) Polyclonal Antibody is a Rabbit antibody targeting Phospho-VE-Cadherin (Tyr731). Anti-Phospho-VE-Cadherin (Tyr731) Polyclonal Antibody can be used in IF,IHC,WB. |
| Synonyms | VE-Cadherin (p-Y731), VE-Cadherin (p-Tyr731), p-VE-Cadherin (Y731), p-VE-Cadherin (Tyr731) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of extracts from HepG2 cells treated with Na3VO4 using Phospho-VE-Cadherin (Tyr731) antibody TMAC-04235. The lane on the right is treated with the antigen-specific peptide. ![]() |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:100-300; IF: 1:50-200 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of Tyrosine731 (H-I-Y(p)-G-Y) derived from Human VE-Cadherin |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 130 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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