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Allopurinol Sodium

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Catalog No. T6376Cas No. 17795-21-0
Alias Sodium allopurinol, Allopurinol sodium salt

Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.

Allopurinol Sodium

Allopurinol Sodium

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Purity: 99.93%
Catalog No. T6376Alias Sodium allopurinol, Allopurinol sodium saltCas No. 17795-21-0
Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$30In StockIn Stock
10 mg$39In StockIn Stock
25 mg$89In StockIn Stock
50 mg$128In Stock-
100 mg$193In Stock-
200 mg$286In Stock-
1 mL x 10 mM (in DMSO)$39In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.93%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.
Targets&IC50
XO:7.82±0.12 μM.
In vitro
EOL-1, human acute myeloid eosinophilic leukemia cell line, was antiproliferative byBI-9564 with EC50 of 800 nM.BRD7 implied as a tumor suppressor and is down-regulated in cancer cells, BI-9564 shows Kd of 73 nM for it, and is >10-fold more selective for BRD9 over the high homologues bromodomain. BI-9564 (<5 μM) shows no activity against 324 kinases, when BI-9564 at 10 μM, an inhibition >40% is observed for only 2 out of 55 GPCRs.
SynonymsSodium allopurinol, Allopurinol sodium salt
Chemical Properties
Molecular Weight159.1
FormulaC5H4N4NaO
Cas No.17795-21-0
Smiles[Na+].O=C1NC=NC2=C1C=NN2
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 30 mg/mL (188.56 mM), Sonication is recommended.
Ethanol: 2 mg/mL (12.57 mM), Sonication is recommended.
H2O: 29 mg/mL (182.28 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/H2O/DMSO
1mg5mg10mg50mg
1 mM6.2854 mL31.4268 mL62.8536 mL314.2678 mL
5 mM1.2571 mL6.2854 mL12.5707 mL62.8536 mL
10 mM0.6285 mL3.1427 mL6.2854 mL31.4268 mL
H2O/DMSO
1mg5mg10mg50mg
20 mM0.3143 mL1.5713 mL3.1427 mL15.7134 mL
50 mM0.1257 mL0.6285 mL1.2571 mL6.2854 mL
100 mM0.0629 mL0.3143 mL0.6285 mL3.1427 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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