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HAPSBC

Name: HAPSBC
Brand: TargetMol
SKU: T82238
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T82238 Copy Product Info

Purity: 99.55%

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HAPSBC is a potent iron chelator of the aromatic hydrazide class with high binding affinity. It induces cellular stress by depriving cells of essential iron, used in cancer metabolism and iron overload research.

HAPSBC

Copy Product Info

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Catalog No. T82238

Cas No. 1376545-81-1

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Pack Size	Price	USA Stock	Global Stock
5 mg	$40	-	In Stock
10 mg	$67	-	In Stock
25 mg	$143	-	In Stock
50 mg	$229	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.55%

Appearance:Solid

Color:White

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Product Introduction

Bioactivity

Description	HAPSBC is a potent iron chelator of the aromatic hydrazide class with high binding affinity. It induces cellular stress by depriving cells of essential iron, used in cancer metabolism and iron overload research.
In vitro	HAPSBC is a lipophilic iron chelator that induces concentration-dependent iron efflux, depriving tumor cells of iron and exerting cytotoxicity [1].

Chemical Properties

Molecular Weight	301.43
Formula	C₁₅H₁₅N₃S₂
Cas No.	1376545-81-1
Smiles	C(=N\NC(SCC1=CC=CC=C1)=S)(\C)/C2=CC=CC=N2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 160 mg/mL (530.8 mM), Sonication is recommmended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3175 mL	16.5876 mL	33.1752 mL	165.8760 mL
5 mM	0.6635 mL	3.3175 mL	6.6350 mL	33.1752 mL
10 mM	0.3318 mL	1.6588 mL	3.3175 mL	16.5876 mL
20 mM	0.1659 mL	0.8294 mL	1.6588 mL	8.2938 mL
50 mM	0.0664 mL	0.3318 mL	0.6635 mL	3.3175 mL
100 mM	0.0332 mL	0.1659 mL	0.3318 mL	1.6588 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc