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Hpn328
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Catalog No. T9901A-787Cas No. 2851862-91-2
Alias Hpn328 (Anti-CD3e & DLL3 & Serum Albumin), Hpn328, Gocatamig, MK-6070
HPN328 is a humanized trispecific T-cell activating construct (TriTAC) that targets CD3 to engage T cells, targets HSA to extend its half-life, and targets DLL3 on tumor cells. It effectively induces T-cell-mediated cytotoxicity against DLL3-expressing small cell lung cancer (SCLC), leading to tumor regression and sustained antitumor immunity. Molecular weight: 53.06 kDa.
Hpn328
Hpn328
😃Good
Catalog No. T9901A-787Alias Hpn328 (Anti-CD3e & DLL3 & Serum Albumin), Hpn328, Gocatamig, MK-6070Cas No. 2851862-91-2
HPN328 is a humanized trispecific T-cell activating construct (TriTAC) that targets CD3 to engage T cells, targets HSA to extend its half-life, and targets DLL3 on tumor cells. It effectively induces T-cell-mediated cytotoxicity against DLL3-expressing small cell lung cancer (SCLC), leading to tumor regression and sustained antitumor immunity. Molecular weight: 53.06 kDa.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | Inquiry | Backorder | |
| 5 mg | Inquiry | Backorder |
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Product Introduction
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Chemical Properties
| Description | HPN328 is a humanized trispecific T-cell activating construct (TriTAC) that targets CD3 to engage T cells, targets HSA to extend its half-life, and targets DLL3 on tumor cells. It effectively induces T-cell-mediated cytotoxicity against DLL3-expressing small cell lung cancer (SCLC), leading to tumor regression and sustained antitumor immunity. Molecular weight: 53.06 kDa. |
| Alias | Hpn328 (Anti-CD3e & DLL3 & Serum Albumin), Hpn328, Gocatamig, MK-6070 |
| Cas No. | 2851862-91-2 |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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