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Anti-MXRA8 Polyclonal Antibody (Synonyms: Limitrin, DICAM, Asp3, Adipocyte-specific protein 3, Adipocyte-spe...)
Catalog No. TMAB-01188 Copy Product Info
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Anti-MXRA8 Polyclonal Antibody is a Rabbit antibody targeting MXRA8. Anti-MXRA8 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Anti-MXRA8 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-01188
Synonyms Limitrin, DICAM, Asp3, Adipocyte-specific protein 3, Adipocyte-specific 3
Anti-MXRA8 Polyclonal Antibody is a Rabbit antibody targeting MXRA8. Anti-MXRA8 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Anti-MXRA8 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Bioactivity
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| Description | Anti-MXRA8 Polyclonal Antibody is a Rabbit antibody targeting MXRA8. Anti-MXRA8 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | Limitrin, DICAM, Asp3, Adipocyte-specific protein 3, Adipocyte-specific 3 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Pig,Cow,Sheep) |
| Verified Activity | 1. Sample: Ovary (Mouse) Lysate at 40 μg MCF-7 (Human) Cell Lysate at 30 μg MD-MB-231 (Human) Cell Lysate at 30 μg Primary: Anti-MXRA8 (TMAB-01188) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 47 kDa Observed band size: 47 kDa 2. Paraformaldehyde-fixed, paraffin embedded (rat cerebellum); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (MXRA8) Polyclonal Antibody, Unconjugated (TMAB-01188) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded (human cerebellum); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (MXRA8) Polyclonal Antibody, Unconjugated (TMAB-01188) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining. 4. Paraformaldehyde-fixed, paraffin embedded (mouse cerebellum); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (MXRA8) Polyclonal Antibody, Unconjugated (TMAB-01188) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining. 5. Sample: Lane 1: Human U-2 OS cell lysates Lane 2: Human HepG2 cell lysates Primary: Anti-MXRA8 (TMAB-01188) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 47 kDa Observed band size: 56 kDa      |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | MXRA8 is a 442 amino acid single-pass type I membrane protein that is implicated in the maintenance and maturation of the blood-brain barrier. Containing two Ig-like V-type (immunoglobulin-like) domains, MXRA8 exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 1p36.33. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma |
| Immunogen | KLH conjugated synthetic peptide: human MXRA8 |
| Antigen Species | Human |
| Gene Name | MXRA8 |
| Gene ID | |
| Protein Name | Matrix remodeling-associated protein 8 |
| Uniprot ID | |
| Biology Area | Other Antibodies |
| Function | May play a role in the maturation and maintenance of blood-brain barrier. |
| Molecular Weight | Theoretical: 47 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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